Evidence map›Paper›PMID 36648891›Full record

ArticleAntibodies (Basel, Switzerland)2023

Therapeutic Phage Display-Derived Single-Domain Antibodies for Pandemic Preparedness.

Janet M Daly, Theam Soon Lim, Kevin C Gough

Abstract read
In one paragraph

Article in Antibodies (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Technologies for Monoclonal Antibody Discovery and Development.International journal of molecular sciences · 2025
    Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Janet M DalySchool of Veterinary Medicine and Science, University of Nottingham, Nottingham NG7 2RD, UK.ORCID 0000-0002-1912-4500
Theam Soon LimInstitute for Research in Molecular Medicine, Universiti Sains Malaysia, Penang 11800, Malaysia.ORCID 0000-0002-0656-3045
Kevin C GoughSchool of Veterinary Medicine and Science, University of Nottingham, Nottingham NG7 2RD, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Driven by necessity, the COVID-19 pandemic caused by SARS-CoV-2 has accelerated the development and implementation of new vaccine platforms and other viral therapeutics. Among these is the therapeutic use of antibodies including single-domain antibodies, in particular the camelid variable heavy-chain fragment (VHH). Such therapies can provide a critical interim intervention when vaccines have not yet been developed for an emerging virus. It is evident that an increasing number of different viruses are emerging and causing epidemics and pandemics with increasing frequency. It is therefore imperative that we capitalize on the experience and knowledge gained from combatting COVID-19 to be better prepared for the next pandemic.

Indexed as

single-domain antibodytherapeuticVHHvirus

Identifiers

PMID36648891
PMCPMC9887586

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.