Evidence map›Paper›PMID 36648835›Full record

ArticleBiotech (Basel (Switzerland))2023

High-Level Production of Soluble Cross-Reacting Material 197 in

Yulia Alexandrovna Khodak, Alexandra Yurievna Ryazanova, Ivan Ivanovich Vorobiev, Alexander Leonidovich Kovalchuk, Nikolay Nikolaevich Ovechko, Petr Gennadievich Aparin

Abstract read
In one paragraph

Article in Biotech (Basel (Switzerland)), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yulia Alexandrovna KhodakFederal State Institution, Federal Research Centre "Fundamentals of Biotechnology", The Russian Academy of Sciences, 119071 Moscow, Russia.
Alexandra Yurievna RyazanovaFederal State Institution, Federal Research Centre "Fundamentals of Biotechnology", The Russian Academy of Sciences, 119071 Moscow, Russia.
Ivan Ivanovich VorobievFederal State Institution, Federal Research Centre "Fundamentals of Biotechnology", The Russian Academy of Sciences, 119071 Moscow, Russia.ORCID 0000-0003-0064-4458
Alexander Leonidovich KovalchukNational Research Center, Institute of Immunology Federal Medical-Biological Agency of Russia, 115522 Moscow, Russia.ORCID 0000-0003-2761-0442
Nikolay Nikolaevich OvechkoNational Research Center, Institute of Immunology Federal Medical-Biological Agency of Russia, 115522 Moscow, Russia.
Petr Gennadievich AparinNational Research Center, Institute of Immunology Federal Medical-Biological Agency of Russia, 115522 Moscow, Russia.

Funding

ATVD-TEAM Co., Ltd. (Moscow, Russia) not applicable
6 · The paper itself

Abstract

Cross-reacting material 197 (CRM197) is a non-toxic mutant of the diphtheria toxin and is widely used as a carrier protein in conjugate vaccines. This protein was first obtained from the supernatant of the mutant

Indexed as

carrier proteinCRM197Escherichia coliprotein expressionprotein solubilitySHuffle strain

Identifiers

PMID36648835
PMCPMC9844443

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.