Evidence map›Paper›PMID 36648833›Full record

ArticleBiotech (Basel (Switzerland))2023

An Optimized CoBRA Method for the Microfluidic Electrophoresis Detection of Breast Cancer Associated

Claire Aibel, Adriana Coll De Peña, Anubhav Tripathi

Open access · goldAbstract read
In one paragraph

Article in Biotech (Basel (Switzerland)), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. The Mechanism of DNA Methylation and miRNA in Breast Cancer.International journal of molecular sciences · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Claire AibelDivision of Biology and Medicine, Brown University, Providence, RI 02912, USA.ORCID 0000-0002-3400-1998
Adriana Coll De PeñaCenter for Biomedical Engineering, School of Engineering, Brown University, Providence, RI 02912, USA.ORCID 0000-0002-5419-4539
Anubhav TripathiCenter for Biomedical Engineering, School of Engineering, Brown University, Providence, RI 02912, USA.
Brown University · US

Funding

PerkinElmer (United States) n/a
6 · The paper itself

Abstract

Although breast cancer screening assays exist, many are inaccessible and have high turnaround times, leaving a significant need for better alternatives. Hypermethylation of tumor suppressor genes is a common epigenetic marker of breast cancer. Methylation tends to occur most frequently in the promoter and first exon regions of genes. Preliminary screening tests are crucial for informing patients whether they should pursue more involved testing. We selected

Indexed as

breast cancercombined bisulfite restriction analysisepigeneticsmethylationmicrofluidic electrophoresis

Identifiers

PMID36648833
PMCPMC9844460
OpenAlexW4315484202

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.