ArticleBiotech (Basel (Switzerland))2023
Novel CaLB-like Lipase Found Using ProspectBIO, a Software for Genome-Based Bioprospection.
Gabriela C Brêda, Priscila E Faria, Yuri S Rodrigues, Priscila B Pinheiro, Maria Clara R Nucci, Pau Ferrer, Denise M G Freire, Rodrigo V Almeida, Rafael D Mesquita
Open access · goldAbstract read
In one paragraphArticle in Biotech (Basel (Switzerland)), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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0citing papers in PubMed
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What it found
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2 · The registryThe trial behind it
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3 · Its place in the literatureWho cites it
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4 · The recordCorrections and comments
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5 · Who and what moneyAuthors and funding
9 authors at 2 institutions in 2 countries.
Gabriela C BrêdaDepartamento de Bioquímica, Instituto de Química, Universidade Federal do Rio de Janeiro, Avenida Athos da Silveira Ramos 149, Rio de Janeiro 21941-909, Brazil.
Priscila E FariaDepartamento de Bioquímica, Instituto de Química, Universidade Federal do Rio de Janeiro, Avenida Athos da Silveira Ramos 149, Rio de Janeiro 21941-909, Brazil.
Yuri S RodriguesDepartamento de Bioquímica, Instituto de Química, Universidade Federal do Rio de Janeiro, Avenida Athos da Silveira Ramos 149, Rio de Janeiro 21941-909, Brazil.
Priscila B PinheiroDepartamento de Bioquímica, Instituto de Química, Universidade Federal do Rio de Janeiro, Avenida Athos da Silveira Ramos 149, Rio de Janeiro 21941-909, Brazil.
Maria Clara R NucciDepartamento de Bioquímica, Instituto de Química, Universidade Federal do Rio de Janeiro, Avenida Athos da Silveira Ramos 149, Rio de Janeiro 21941-909, Brazil.
Pau FerrerDepartment of Chemical, Biological and Environmental Engineering, Universitat Autònoma de Barcelona, 08193 Bellaterra, Catalonia, Spain.ORCID 0000-0002-5287-4127 Denise M G FreireDepartamento de Bioquímica, Instituto de Química, Universidade Federal do Rio de Janeiro, Avenida Athos da Silveira Ramos 149, Rio de Janeiro 21941-909, Brazil.ORCID 0000-0002-8298-5936 Rodrigo V AlmeidaDepartamento de Bioquímica, Instituto de Química, Universidade Federal do Rio de Janeiro, Avenida Athos da Silveira Ramos 149, Rio de Janeiro 21941-909, Brazil.ORCID 0000-0002-0164-6044 Rafael D MesquitaDepartamento de Bioquímica, Instituto de Química, Universidade Federal do Rio de Janeiro, Avenida Athos da Silveira Ramos 149, Rio de Janeiro 21941-909, Brazil.ORCID 0000-0002-2882-3362 Universidade Federal do Rio de Janeiro · BRUniversitat Autònoma de Barcelona · ES
Funding
Coordenação de Aperfeicoamento de Pessoal de Nível Superior PEF PhD fellowshipFundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro E-26/110.178/2014National Council for Scientific and Technological Development 158956/2015-0
6 · The paper itselfAbstract
Enzymes have been highly demanded in diverse applications such as in the food, pharmaceutical, and industrial fuel sectors. Thus, in silico bioprospecting emerges as an efficient strategy for discovering new enzyme candidates. A new program called ProspectBIO was developed for this purpose as it can find non-annotated sequences by searching for homologs of a model enzyme directly in genomes. Here we describe the ProspectBIO software methodology and the experimental validation by prospecting for novel lipases by sequence homology to
Indexed as
bioprospectionCaLBfunctional characterizationprotein
Identifiers
PMID36648832
PMCPMC9844320
OpenAlexW4316928065
What OpenQuestion holds
Textmetadata
LicenceCC BY
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