ArticleUrolithiasis2023
Understanding the ablation rate of Holmium:YAG and thulium fiber lasers. Perspectives from an in vitro study.
Article in Urolithiasis, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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18 citing papers in PubMed, 17 citations in OpenAlex.
- Soft Tissue Safety Assessment of Pulsed Solid-State Thulium:YAG Versus Holmium:YAG Lasers: A Quantitative Porcine Model Simulation.Lasers in surgery and medicine · 2026Article
- Technique-stratified whole-stone laser energy consumption during RIRS using a 150-W Ho: YAG laser.Urolithiasis · 2026Article
- Comparison of TFL and high-power Ho: YAG lasers with multiple pulse modulations: an in vitro study.World journal of urology · 2026Article
- Efficacy of thulium fiber laser litothripsy on large renal stones (> 1000 mm³) according to Hounsfield units: a prospective single-center study.BMC urology · 2026Article
- Optimal thulium fiber laser parameters for non-impacted stone lithotripsy: an in-vitro and ex-vivo evaluation.Urolithiasis · 2026Article
- Exploring the influence of laser parameters on retropulsion and ablation rate in thulium fiber laser lithotripsy: an in vitro study.International urology and nephrology · 2025Article
- Iatrogenic upper urinary tract injuries during ureteroscopy for urolithiasis: a comprehensive review on incidence, mechanisms and preventative strategies.Nature reviews. Urology · 2025Review
- Comparative analysis of thulium fiber and holmium: YAG lasers on retropulsion and stone migration in ureteroscopic lithotripsy: real-world data.Lasers in medical science · 2025Article
- Temperature variations with Ho: YAG and thulium fiber lasers, including advanced fragmentation pulse (AFP) technology: an experimental analysis.World journal of urology · 2025Article
- Steady-state versus burst lasing techniques for thulium fiber laser.World journal of urology · 2024Article
- Comparative Analyses and Ablation Efficiency of Thulium Fiber Laser by Stone Composition.The Journal of urology · 2024Article
- High-power Holmium:Yag lithotripsy in bladder urolithiasis: Is it safe and effective? A combined clinical and experimental study.Arab journal of urology · 2024Article
- Effect of Ho:YAG laser on kidney tissue with Virtual BasketWorld journal of urology · 2023Article
- Femtosecond laser lithotripsy: a novel alternative for kidney stone treatment? Evaluating the safety and effectiveness in an ex vivo study.Urolithiasis · 2023Article
- False discovery rate in laser studies.World journal of urology · 2023Article
- Innovations in Kidney Stone Removal.Research and reports in urology · 2023Review
- Evaluation of pulse modulation settings for optimal pop-dusting efficiency using the Quanta Litho 150 laser: AnUrology annalsArticle
- Thulium fiber laser versus high-power holmium laser for renal stones: a systematic review and meta-analysis of high-quality studies.Therapeutic advances in urologyArticle
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Authors and funding
6 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study sought to analyze the ablation rates of Holmium:YAG (Ho:YAG) and thulium fiber laser (TFL) under different settings combinations. Lasering was carried out by a computed spiral pattern through a stepper motor bearing a laser fiber. BegoStones were placed inside a water container and lasered therein and the ablation rate was calculated. Different combinations were tested for ~12 Watts (W) for Ho:YAG and TFL lasers. Further 25 W combination for TFL were conducted testing higher frequencies. One-hundred-one experiments were conducted. Under ~12 W, the highest ablation rate for Ho:YAG was obtained with 40 Hz/0.3 J, and Virtual Basket™ (VB) emission mode [114.35 (88.30 - 126.40) mg/min] whereas for TFL, using 40 Hz/0.3 J, and long pulse [143.40 (137.40 - 146) mg/min]. A matched-comparison for 12 Hz/1 J settings showed that TFL outperformed Ho:YAG using medium pulse [63.30 (55.30 - 81.30) vs 132.00 (115.70 - 228.60) mg/min, p=0.016] and long pulse [62.90 (51.60 - 78.90) vs 134.70 (110.60 - 149.30) mg/min, p=0.016]. In the 40 Hz/0.3 J settings, TFL outperformed Ho:YAG (p=0.034). Nonetheless, Ho:YAG with VB's ablation rate increased [114.35 (88.30 - 126.40)], being comparable to that of TFL with medium pulse [127.5 (88.90 - 141.70)] (p=0.400). In TFL 25 W experiments, the ablation rate of 500 Hz / 0.05 J, was higher than those of 1000 Hz / 0.025 J (p=0.049). TFL ablation rate is higher than that of Ho:YAG. Moreover, the Virtual Basket™ emission mode, increased Ho:YAG ablation rates, resulting reaching similar to that of TFL in certain modalities.
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