Evidence map›Paper›PMID 36648232›Full record

ArticleInfection and immunity2023

Selenomonas sputigena Interactions with Gingival Epithelial Cells That Promote Inflammation.

Colin G Hawkes, Annie N Hinson, Aruna Vashishta, Curtis B Read, Jason A Carlyon, Richard J Lamont, Silvia M Uriarte, Daniel P Miller

Open access · greenAbstract read
In one paragraph

Article in Infection and immunity, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
5.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 25 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Draft genome sequence ofMicrobiology resource announcements · 2025
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Colin G HawkesPhilips Institute for Oral Health Research, Virginia Commonwealth University School of Dentistry, Richmond, Virginia, USA.
Annie N HinsonDepartment of Microbiology and Immunology, Virginia Commonwealth University School of Medicine, Richmond, Virginia, USA.
Aruna VashishtaDepartment of Oral Immunology and Infectious Diseases, University of Louisville School of Dentistry, Louisville, Kentucky, USA.
Curtis B ReadDepartment of Microbiology and Immunology, Virginia Commonwealth University School of Medicine, Richmond, Virginia, USA.
Jason A CarlyonDepartment of Microbiology and Immunology, Virginia Commonwealth University School of Medicine, Richmond, Virginia, USA.ORCID 0000-0003-2778-5066
Richard J LamontDepartment of Oral Immunology and Infectious Diseases, University of Louisville School of Dentistry, Louisville, Kentucky, USA.ORCID 0000-0002-3147-5039
Silvia M UriarteDepartment of Oral Immunology and Infectious Diseases, University of Louisville School of Dentistry, Louisville, Kentucky, USA.
Daniel P MillerDepartment of Microbiology and Immunology, Virginia Commonwealth University School of Medicine, Richmond, Virginia, USA.ORCID 0000-0002-1332-5870
Virginia Commonwealth University · USUniversity of Louisville · US

Funding

Virus Vector Shared ResourceP30CA016059 · NCI · VIRGINIA COMMONWEALTH UNIVERSITY · PI Kim Felder Rhoads · 1985 to 2026
$51.0M
The roles of ceramide and its derivatives in A. phagocytophilum pathogenesisR01AI139072 · NIAID · VIRGINIA COMMONWEALTH UNIVERSITY · PI CHARLES E. CHALFANT, Jason A Carlyon · 2018 to 2026
$5.7M
P GINGIVALIS INTERACTIONS WITH GINGIVAL EPITHELIAL CELLSR01DE011111 · NIDCR · UNIVERSITY OF WASHINGTON · PI HARIBABU BODDULURI, Richard J Lamont · 1995 to 2026
$5.4M
P.gingivalis Interactions with Gingival Epithelial CellsR37DE011111 · NIDCR · UNIVERSITY OF LOUISVILLE · PI LAMONT, RICHARD J · 2009 to 2018
$3.6M
Polymicrobial Synergy between Treponema denticola and Porphyromonas gingivalisR00DE028346 · NIDCR · VIRGINIA COMMONWEALTH UNIVERSITY · PI MILLER, DANIEL PATRICK · 2020 to 2022
$747k
Polymicrobial Synergy between Treponema denticola and Porphyromonas gingivalisK99DE028346 · NIDCR · UNIVERSITY OF LOUISVILLE · PI MILLER, DANIEL PATRICK · 2018 to 2019
$214k
NCI NIH HHS P30 CA016059NIAID NIH HHS R01 AI139072NIDCR NIH HHS K99 DE028346NIDCR NIH HHS R00 DE028346NIDCR NIH HHS R01 DE011111NIDCR NIH HHS R37 DE011111
6 · The paper itself

Abstract

Increased prevalence and abundance of Selenomonas sputigena have been associated with periodontitis, a chronic inflammatory disease of tooth-supporting tissues, for more than 50 years. Over the past decade, molecular surveys of periodontal disease using 16S and shotgun metagenomic sequencing approaches have confirmed the disease association of classically recognized periodontal pathogens such as Porphyromonas gingivalis, Treponema denticola, and Tannerella forsythia while highlighting previously underappreciated organisms such as Filifactor alocis and S. sputigena. Despite abundant clinical association between

Indexed as

Periodontal DiseasesPeriodontitisCytokinesEpithelial CellsHumansInflammationPorphyromonas gingivalisSelenomonasCytokinescytokinegingivalinflammationpathogenesisperiodontal diseaseperiodontal pathogenperiodontitisSelenomonas

Identifiers

PMID36648232
PMCPMC9933688
OpenAlexW4316814914

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.