Evidence map›Paper›PMID 36648152›Full record

Observational studyThe Journal of urology2023

Risk Factors for Increased Stent-associated Symptoms Following Ureteroscopy for Urinary Stones: Results From STENTS.

Jonathan D Harper, Alana C Desai, Naim M Maalouf, Hongqiu Yang, Jodi A Antonelli, Gregory E Tasian, H Henry Lai, Peter P Reese, Michele Curatolo, Ziya Kirkali and 3 more

Open access · greenAbstract readObservational StudyMulticenter Study
In one paragraph

Observational study in The Journal of urology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
7.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 27 citations in OpenAlex.

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  17. Recent development and future application of biodegradable ureteral stents.Frontiers in bioengineering and biotechnology · 2024
    Review
  18. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 7 institutions in 3 countries.

Jonathan D HarperDepartment of Urology, University of Washington, Seattle, Washington.
Alana C DesaiDepartment of Surgery (Urologic Surgery), Washington University in St Louis, St Louis, Missouri.
Naim M MaaloufDepartment of Internal Medicine and Charles and Jane Pak Center for Mineral Metabolism and Clinical Research, University of Texas Southwestern Medical Center, Dallas, Texas.
Hongqiu YangDuke Clinical Research Institute, Duke University School of Medicine, Durham, North Carolina.
Jodi A AntonelliDepartment of Surgery (Urology), Duke Surgical Center for Outcomes Research & Equity in Surgery, Duke University School of Medicine, Durham, North Carolina.
Gregory E TasianDivision of Urology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
H Henry LaiDepartment of Surgery (Urologic Surgery), Washington University in St Louis, St Louis, Missouri.
Peter P ReeseDepartment of Medicine, Renal Division, University of Pennsylvania, Philadelphia, Pennsylvania.
Michele CuratoloDepartment of Anesthesiology & Pain Medicine, University of Washington, Seattle, Washington.
Ziya KirkaliNational Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, Maryland.
Hussein R Al-KhalidiDuke Clinical Research Institute, Duke University School of Medicine, Durham, North Carolina.
Hunter WessellsDepartment of Urology, University of Washington, Seattle, Washington.
Charles D ScalesDuke Clinical Research Institute, Duke University School of Medicine, Durham, North Carolina.ORCID 0000-0002-7887-0204
Duke University · USUniversity of Washington · USWashington University in St. Louis · USCalifornia University of Pennsylvania · USChildren's Hospital of Philadelphia · USMineral Resources · AUNational Institute of Diabetes and Digestive and Kidney Diseases · US

Funding

Urinary Stone Disease Research Network: Scientific Data Research CenterU01DK110988 · NIDDK · DUKE UNIVERSITY · PI AL-KHALIDI, HUSSEIN, SCALES, CHARLES D · 2016 to 2020
$6.9M
Optimizing Fluid Therapy and Stent Management in Children and Adults with NephrolithiasisU01DK110994 · NIDDK · UT SOUTHWESTERN MEDICAL CENTER · PI MAALOUF, NAIM M · 2016 to 2024
$5.3M
Harnessing Behavior to Decrease Urinary Stone Disease Morbidity Research ProjectU01DK110961 · NIDDK · CHILDREN'S HOSP OF PHILADELPHIA · PI REESE, PETER PHILIP, TASIAN, GREGORY EDWARD · 2016 to 2024
$5.3M
Extension of Urinary Stone Disease Research Network (USDRN) at Washington UniversityU01DK110986 · NIDDK · WASHINGTON UNIVERSITY · PI LAI, HING HUNG HENRY · 2016 to 2024
$5.2M
UW USDRN Clinical CenterU01DK110954 · NIDDK · UNIVERSITY OF WASHINGTON · PI HARPER, JONATHAN D., WESSELLS, HUNTER · 2016 to 2024
$4.9M
Urinary Stone Disease Research Network: Scientific Data Research CenterU24DK110988 · NIDDK · DUKE UNIVERSITY · PI AL-KHALIDI, HUSSEIN, SCALES, CHARLES D · 2022 to 2024
$4.1M
NIDDK NIH HHS U01 DK110954NIDDK NIH HHS U01 DK110961NIDDK NIH HHS U01 DK110986NIDDK NIH HHS U01 DK110988NIDDK NIH HHS U01 DK110994NIDDK NIH HHS U24 DK110988
6 · The paper itself

Abstract

purposeThe STudy to Enhance uNderstanding of sTent-associated Symptoms sought to identify risk factors for pain and urinary symptoms, as well as how these symptoms interfere with daily activities after ureteroscopy for stone treatment. MATERIALS AND

methodsThis prospective observational cohort study enrolled patients aged ≥12 years undergoing ureteroscopy with ureteral stent for stone treatment at 4 clinical centers. Participants reported symptoms at baseline; on postoperative days 1, 3, 5; at stent removal; and day 30 post-stent removal. Outcomes of pain intensity, pain interference, urinary symptoms, and bother were captured with multiple instruments. Multivariable analyses using mixed-effects linear regression models were identified characteristics associated with increased stent-associated symptoms.

resultsA total of 424 participants were enrolled. Mean age was 49 years (SD 17); 47% were female. Participants experienced a marked increase in stent-associated symptoms on postoperative day 1. While pain intensity decreased ∼50% from postoperative day 1 to postoperative day 5, interference due to pain remained persistently elevated. In multivariable analysis, older age was associated with lower pain intensity (

conclusionsIn this multicenter cohort, interference persisted even as pain intensity decreased. Patient factors (eg, age, depression) rather than surgical factors were associated with symptom intensity. These findings provide a foundation for patient-centered care and highlight potential targets for efforts to mitigate the burden of stent-associated symptoms.

Indexed as

Ureteral CalculiUrinary CalculiUrolithiasisFemaleHumansMaleMiddle AgedPostoperative PainProspective StudiesRisk FactorsStentsUreteroscopypain, urinary calculipatient outcome assessmentstentsureteroscopy

Identifiers

PMID36648152
PMCPMC10336697
OpenAlexW4316927880

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.