Evidence map›Paper›PMID 36647686›Full record

Observational studyInternational wound journal2023

Comparison of vitamin D levels in diabetes mellitus patients with and without diabetic foot ulcers: An analytical observational study in Jakarta, Indonesia.

Mufqi Handaru Priyanto, Lili Legiawati, Siti Rizny F Saldi, Em Yunir, Eliza Miranda

Abstract readObservational Study
In one paragraph

Observational study in International wound journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Micronutrient status of patients with diabetic foot: A systematic review.Asia Pacific journal of clinical nutrition · 2025
    Pooled it
  2. Pooled it
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  4. Pooled it
  5. Article
  6. Article
  7. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mufqi Handaru PriyantoDepartment of Dermatology and Venereology, Faculty of Medicine Universitas Indonesia, Dr. Cipto Mangunkusumo National Hospital, Central Jakarta, Indonesia.
Lili LegiawatiDepartment of Dermatology and Venereology, Faculty of Medicine Universitas Indonesia, Dr. Cipto Mangunkusumo National Hospital, Central Jakarta, Indonesia.
Siti Rizny F SaldiClinical Epidemiology and Evidence-Based Medicine Unit, Faculty of Medicine Universitas Indonesia, Dr. Cipto Mangunkusumo National Hospital, Central Jakarta, Indonesia.
Em YunirDepartment of Internal Medicine, Faculty of Medicine Universitas Indonesia, Dr. Cipto Mangunkusumo National Hospital, Central Jakarta, Indonesia.
Eliza MirandaDepartment of Dermatology and Venereology, Faculty of Medicine Universitas Indonesia, Dr. Cipto Mangunkusumo National Hospital, Central Jakarta, Indonesia.

Funding

Universitas Indonesia NKB-4748/UN2.RST/HKP.05.00/2020
6 · The paper itself

Abstract

Diabetic foot ulcer (DFU) is a form of chronic wound which becomes a serious complication in diabetes mellitus (DM). Recently, the role of vitamin D on T cell-mediated immunity, pancreatic insulin secretion, and its mechanism on cell growth and healing processes have been reported. This study aims to compare the vitamin D level of DM patients with DFU and without DFU to assess the duration and severity of DFU and its correlation with vitamin D levels. The sociodemographic characteristics and DFU duration were documented. The severity was examined in accordance with PEDIS classification. 25-hydroxyvitamin D (25[OH]D) was analysed using in-vitro chemiluminescent immunoassay (CLIA). Statistical analysis was performed and the P-value <.05 was considered as statistically significant. The vitamin D levels in DM patients with and without DFU were 8.90 ng/mL (6.52-10.90) and 16.25 ng/mL (13-19.59), respectively, with P < .001. There was no correlation between the duration of DFU and DFU severity by PEDIS score with vitamin D levels. Vitamin D levels in DM patients with DFU are lower than those in patients without DFU. However, there was insufficient evidence to conclude that there is no correlation between the DFU duration and DFU severity by PEDIS score with vitamin D levels.

Indexed as

Diabetes MellitusDiabetic FootVitamin DAgedFemaleHumansIndonesiaMaleMiddle AgedRisk FactorsSeverity of Illness IndexTime FactorsVitamin DDFU durationDFU severitydiabetic foot ulcervitamin D

Identifiers

PMID36647686
PMCPMC10333004

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.