Evidence map›Paper›PMID 36647573›Full record

ArticleChemical research in toxicology2023

Characterization of a Novel Thermostable DNA Lyase Used To Prepare DNA for Next-Generation Sequencing.

Tuvshintugs Baljinnyam, James W Conrad, Mark L Sowers, Bruce Chang-Gu, Jason L Herring, Linda C Hackfeld, Kangling Zhang, Lawrence C Sowers

Open access · hybridAbstract read
In one paragraph

Article in Chemical research in toxicology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Tuvshintugs BaljinnyamDepartment of Pharmacology and Toxicology, University of Texas Medical Branch, 301 University Boulevard, Galveston, Texas77555, United States.ORCID 0000-0001-8664-9318
James W ConradDepartment of Pharmacology and Toxicology, University of Texas Medical Branch, 301 University Boulevard, Galveston, Texas77555, United States.
Mark L SowersDepartment of Pharmacology and Toxicology, University of Texas Medical Branch, 301 University Boulevard, Galveston, Texas77555, United States.ORCID 0000-0001-6474-017X
Bruce Chang-GuDepartment of Pharmacology and Toxicology, University of Texas Medical Branch, 301 University Boulevard, Galveston, Texas77555, United States.
Jason L HerringDepartment of Pharmacology and Toxicology, University of Texas Medical Branch, 301 University Boulevard, Galveston, Texas77555, United States.
Linda C HackfeldDepartment of Pharmacology and Toxicology, University of Texas Medical Branch, 301 University Boulevard, Galveston, Texas77555, United States.
Kangling ZhangDepartment of Pharmacology and Toxicology, University of Texas Medical Branch, 301 University Boulevard, Galveston, Texas77555, United States.ORCID 0000-0003-2151-9218
Lawrence C SowersDepartment of Pharmacology and Toxicology, University of Texas Medical Branch, 301 University Boulevard, Galveston, Texas77555, United States.
The University of Texas Medical Branch at Galveston · US

Funding

Translational Research Support CoreP30ES030285 · NIEHS · BAYLOR COLLEGE OF MEDICINE · PI Casey W Wright · 2019 to 2026
$14.7M
Cytosine Deamination Adducts and Cancer EtiologyR01CA228085 · NCI · UNIVERSITY OF TEXAS MED BR GALVESTON · PI SOWERS, LAWRENCE C · 2019 to 2023
$2.1M
NCI NIH HHS R01 CA228085
6 · The paper itself

Abstract

Recently, we constructed a hybrid thymine DNA glycosylase (hyTDG) by linking a 29-amino acid sequence from the human thymine DNA glycosylase with the catalytic domain of DNA mismatch glycosylase (MIG) from

Indexed as

DNA GlycosylasesLyasesThymine DNA GlycosylaseDNADNA RepairHigh-Throughput Nucleotide SequencingHumansSubstrate SpecificityDNADNA GlycosylasesLyasesThymine DNA Glycosylase

Identifiers

PMID36647573
PMCPMC9945173
OpenAlexW4316672795

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.