Evidence map›Paper›PMID 36647482›Full record

ArticleJournal of thoracic disease2022

Pericoronary fat attenuation index is associated with plaque parameters and stenosis severity in patients with acute coronary syndrome: a cross-sectional study.

Runzhi Zhang, Zhiguo Ju, Yuanyuan Li, Yan Gao, Hui Gu, Ximing Wang

Abstract read
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Article in Journal of thoracic disease, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

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0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

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  17. Correlation Between Fat Attenuation Index and Plaque Parameters in Coronary CT Angiography: An Observational Study in Stable Coronary Artery Disease.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
    Observational
4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Runzhi ZhangDepartment of Radiology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China.
Zhiguo JuCollege of Medical Imaging, Shanghai University of Medicine and Health Science, Shanghai, China.
Yuanyuan LiDepartment of Radiology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China.
Yan GaoDepartment of Radiology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China.
Hui GuDepartment of Radiology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China.
Ximing WangDepartment of Radiology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The pericoronary fat attenuation index (FAI) is a novel imaging biomarker of coronary inflammation, which is closely related to development and progression of coronary artery disease (CAD). However, there are limited reports on whether elevated pericoronary FAI values from coronary computed tomography angiography (CCTA) were associated with plaque parameters and coronary stenosis in patients with acute coronary syndrome (ACS). We aimed to assessed that FAI helps to identify high risk of CAD. Methods: The clinical diagnosis confirmed to the American Heart Association guidelines for ACS. The lesion-specific pericoronary FAI and plague parameters were measured using QAngioCT software. Using a Hounsfield unit (HU) of -70.1 as the threshold value, lesions with a lesion-specific pericoronary FAI value ≥-70.1 HU were allocated to the FAI-positive group and those with a FAI value <-70.1 HU were allocated to the FAI-negative group. The patients were divided into four stenosis groups according to the coronary angiography (CAG) results, and differences in the FAI values among the four groups were analyzed. Results: A retrospective analysis of 127 ACS patients, including 299 lesions, who underwent CCTA and CAG successively was conducted. The prevalence of vulnerable plaques increased significantly in the FAI-positive group (49.35% Conclusions: The FAI was identified as a novel imaging biomarker of coronary inflammation that is correlated with vulnerable plaque features and stenosis severity.

Indexed as

Coronary artery disease (CAD)coronary computed tomography angiography (CCTA)perivascular adipose tissuevulnerable plagues

Identifiers

PMID36647482
PMCPMC9840010

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.