Evidence map›Paper›PMID 36647463›Full record

ArticleJournal of thoracic disease2022

Preoperative albumin corrected anion gap is associated with in-hospital and long-term mortality in patients undergoing coronary artery bypass grafting in a retrospective cohort study.

Ruiling Wang, Jiale Li, Huimin Chen, Zezhou Xiao, Rongning Xu, Yu Hu, Sikai Chen, Xiaowu Wang, Shaoyi Zheng

Open access · diamondAbstract read
In one paragraph

Article in Journal of thoracic disease, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Ruiling Wang *Department of Cardiovascular Surgery, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Jiale Li *Department of Cardiovascular Surgery, Zhujiang Hospital, Southern Medical University, Guangzhou, China.
Huimin ChenDepartment of Cardiovascular Surgery, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Zezhou XiaoDepartment of Cardiovascular Surgery, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Rongning XuDepartment of Cardiovascular Surgery, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Yu HuDepartment of Cardiovascular Surgery, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Sikai ChenDepartment of Cardiovascular Surgery, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Xiaowu WangDepartment of Cardiovascular Surgery, Zhujiang Hospital, Southern Medical University, Guangzhou, China.
Shaoyi ZhengDepartment of Cardiovascular Surgery, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Southern Medical University · CNNanfang Hospital · CNZhujiang Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Coronary artery disease remains a global health concern and the leading cause of death. Till today, coronary artery bypass grafting (CABG) is one of the main treatment strategies for coronary artery disease, especially for Multivessel coronary disease or complex coronary lesions. The present study aimed to explore the relationship of preoperative albumin corrected anion gap (ACAG) with mortality in all those patients who undergoing CABG. Methods: All the patients undergoing CABG were included in the study. All clinical data were collected from CareVue and MetaVision system. The predictive value of ACAG for mortality was determined by receiver operating characteristic (ROC) curves survival curves were estimated using the Kaplan-Meier method. Multivariate regression models were constructed to determine the association of ACAG with mortality. Results: A total of 2,180 patients were identified and divided into a high ACAG group (ACAG ≥16.0 mmol/L) and low ACAG group (ACAG <16.0 mmol/L) according to the ROC analysis. Patients in the high ACAG group were older and presented with more comorbidities and concomitant valvular surgeries. Further more, in the high ACAG group, we observed a higher length of stay in the intensive care unit [3.88 (2.15, 7.09) Conclusions: Preoperative ACAG is an independent risk factor for in-hospital and long-term mortality in CABG patients. A higher ACAG may relate to severe coronary artery stenosis and cardiac dysfunction, which is more likely to lead to a postoperative systemic inflammatory response, microcirculation disorder, and subsequent complications.

Indexed as

albumin corrected anion gap (ACAG)Coronary artery bypass grafting (CABG)mortality

Identifiers

PMID36647463
PMCPMC9840039
OpenAlexW4313330622

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.