SynthesisPeerJ2023
Effects of high-intensity interval exercise on cardiac troponin elevation when comparing with moderate-intensity continuous exercise: a systematic review and meta-analysis.
Synthesis in PeerJ, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 7 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 7 syntheses or guidelines pooled it, 24 citations in OpenAlex.
- Effects of virtual reality exercise on social skills and emotional recognition among children with autism spectrum disorder: a meta-analysis of randomized controlled trials.BMC psychology · 2026Pooled it
- Pooled it
- Pooled it
- Effects of the combination of exercise with noninvasive brain stimulation on motor function and spasticity in children with cerebral palsy: A systematic review and meta-analysis.European journal of pediatrics · 2025Pooled it
- Natural history of progressive vision loss in Bietti crystalline dystrophy: a model-based meta-analysis.BMJ open ophthalmology · 2025Pooled it
- The impact of digital healthcare systems on pain and body function in patients with knee joint pain: a systematic review and meta-analysis.Scientific reports · 2024Pooled it
- The Effects of Combined Exercise with Citrulline Supplementation on Body Composition and Lower Limb Function of Overweight Older Adults: A Systematic Review and Meta-Analysis.Journal of sports science & medicine · 2023Pooled it
- Effects of breaking up prolonged sitting via exercise snacks intervention on the body composition and plasma metabolomics of sedentary obese adults: a randomized controlled trial.Endocrine journal · 2025Trial
- The impact of probiotic supplementation on mucosal immunity and oxidative stress after high-intensity exercise among athletes: a meta-analysis.BMC sports science, medicine & rehabilitation · 2026Article
- The effects of rebound exercise on body mass index and balance in overweight and obese adults: a meta-analysis.Endocrine connections · 2026Article
- The effect of exercise intervention on balance and executive function in children with autism spectrum disorder: a meta-analysis.BMC sports science, medicine & rehabilitation · 2025Article
- The Effect of Low-Intensity Interval Exercise with Blood Flow Restriction on Plasma Cardiac Troponin: A Cross-Design Trial.Anatolian journal of cardiology · 2024Article
- Application of exercise therapy in patients with chronic kidney disease-induced muscle atrophy: a scoping review.BMC sports science, medicine & rehabilitation · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 6 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: This systematic review and meta-analysis aimed to compare the effects of high-intensity interval exercise (HIIE) with different recovery modes versus moderate-intensity continuous exercise (MICE) on cardiac troponin (cTn) elevation. Methodology: A literature search was conducted in four databases: Scopus, PubMed, EBSCO and Web of Science from January 2010 to June 2022. The articles were screened, evaluated for quality before data were extracted. The review protocol was registered at PROSPERO (CRD42021245649). Standardized mean differences (SMD) of peak cTn were analyzed with a 95% confidence interval (95% CI) using Revman 5.4 software. Results: Six studies satisfied the inclusion criteria with a total of 92 and 79 participants for HIIE and MICE, respectively. Overall, there was no significant difference between HIIE and MICE in the elevation of cardiac troponin T (SMD: 0.41 [95% CI [-0.21, 1.03]], Conclusions: There was no significant difference between HIIE and MICE in the elevation of cardiac troponin T. However, HIIE with passive recovery elicited more cardiac troponin T elevation than MICE, which should be considered when developing exercise programs.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.