Evidence map›Paper›PMID 36647399›Full record

ArticleJournal of clinical and experimental hepatology

Liver Stiffness Values in Persons with Normal Histology.

Deepak Sharma, Narendra S Choudhary, Swapnil Dhampalwar, Neeraj Saraf, Ajay Duseja, Dheeraj Gautam, Arvinder S Soin, Randhir Sud

Open access · bronzeAbstract read
In one paragraph

Article in Journal of clinical and experimental hepatology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Deepak SharmaInstitute of Digestive and Hepatobiliary Sciences, Medanta The Medicity, Gurugram, India.
Narendra S ChoudharyInstitute of Liver Transplantation and Regenerative Medicine, Medanta The Medicity, Gurugram, India.
Swapnil DhampalwarInstitute of Liver Transplantation and Regenerative Medicine, Medanta The Medicity, Gurugram, India.
Neeraj SarafInstitute of Liver Transplantation and Regenerative Medicine, Medanta The Medicity, Gurugram, India.
Ajay DusejaDepartment of Hepatology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Dheeraj GautamDepartment of Pathology, Medanta The Medicity, Gurugram, India.
Arvinder S SoinInstitute of Liver Transplantation and Regenerative Medicine, Medanta The Medicity, Gurugram, India.
Randhir SudInstitute of Digestive and Hepatobiliary Sciences, Medanta The Medicity, Gurugram, India.
Medanta The Medicity · INMedanta The Medicity · INPost Graduate Institute of Medical Education and Research · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and aims: Most studies to date have focused on liver stiffness measurement (LSM) in patients with different chronic liver diseases, and normal LSM is defined based on normal liver function tests or the absence of fibrosis. Very few studies have defined LSM based on completely normal liver biopsies. The current study was done to define the distribution of LSM values in individuals with normal liver biopsies. Methods: All prospective liver donors presenting to Medanta, the Medicity hospital between September 2020 and September 2021 fulfilling the eligibility criteria were included in this study. Results: A total of 63 donors (36 females and 27 males) were included in the study, 37 (58.7%) donors had normal liver biopsies, and 26 (41.2%) donors showed the presence of non-alcoholic fatty liver disease. LSM values in the normal liver histology group were 5.01 ± 1.99 kPa by the M probe and 5.34 ± 2.25 kPa by the XL probe. Even though the correlation was weak (r = 0.29, Conclusions: LSM value in the biopsy-proven normal liver histology group was 5.01 ± 1.99 by the M probe and 5.34 ± 2.25 by the XL probe.

Indexed as

FibroScanLDLT, living donor liver transplantationliver biopsyLSM, liver stiffness measurementNAFLD, non-alcoholic fatty liver diseasenormalstiffnessTE, transient elastography

Identifiers

PMID36647399
PMCPMC9840077
OpenAlexW4309093110

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.