Evidence map›Paper›PMID 36647381›Full record

ReviewiScience2023

Large-scale multimodal surface neural interfaces for primates.

Tiphaine Belloir, Sergio Montalgo-Vargo, Zabir Ahmed, Devon J Griggs, Shawn Fisher, Timothy Brown, Maysamreza Chamanzar, Azadeh Yazdan-Shahmorad

Open access · goldAbstract readReview
In one paragraph

Review in iScience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 14 citations in OpenAlex.

  1. Towards maximizing optical access through Smart Dura.Journal of neural engineering · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. A Neural Implant Design Toolbox for Nonhuman Primates.Journal of visualized experiments : JoVE · 2024
    Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Tiphaine BelloirDepartment of Bioengineering, University of Washington, Seattle, WA, USA.
Sergio Montalgo-VargoDepartment of Electrical and Computer Engineering, Carnegie Mellon University, Pittsburgh, PA, USA.
Zabir AhmedDepartment of Electrical and Computer Engineering, Carnegie Mellon University, Pittsburgh, PA, USA.
Devon J GriggsWashington National Primate Research Center, Seattle, WA, USA.
Shawn FisherDepartment of Bioengineering, University of Washington, Seattle, WA, USA.
Timothy BrownDepartment of Bioethics & Humanities, University of Washington, Seattle, WA, USA.
Maysamreza ChamanzarDepartment of Electrical and Computer Engineering, Carnegie Mellon University, Pittsburgh, PA, USA.
Azadeh Yazdan-ShahmoradDepartment of Bioengineering, University of Washington, Seattle, WA, USA.
University of Washington · USCarnegie Mellon University · US

Funding

Washington National Primate Research CenterP51OD010425 · OD · UNIVERSITY OF WASHINGTON · PI Mari Ostendorf · 2012 to 2026
$201.8M
WaNPRC Macaca nemestrina SPF Breeding ColonyU42OD011123 · OD · UNIVERSITY OF WASHINGTON · PI CHARLOTTE HOTCHKISS · 2012 to 2026
$34.4M
Engineering neuroplasticity using volitional control of activity-dependent optogenetic stimulation in macaque sensorimotor cortexR01NS119395 · NINDS · UNIVERSITY OF WASHINGTON · PI YAZDAN SHAHMORAD, AZADEH · 2021 to 2025
$3.9M
Smart Dura: A Functional Large-scale, High-Density Optoelectric Dura for Non-Human PrimatesR01NS116464 · NINDS · CARNEGIE-MELLON UNIVERSITY · PI CHAMANZAR, MAYSAMREZA · 2020 to 2024
$2.0M
Integrative Training in Neural InterfacingT32EB029365 · NIBIB · CARNEGIE-MELLON UNIVERSITY · PI HE, BIN · 2021 to 2025
$1.0M
NIBIB NIH HHS T32 EB029365NIH HHS P51 OD010425NINDS NIH HHS R01 NS116464NINDS NIH HHS R01 NS119395
6 · The paper itself

Abstract

Deciphering the function of neural circuits can help with the understanding of brain function and treating neurological disorders. Progress toward this goal relies on the development of chronically stable neural interfaces capable of recording and modulating neural circuits with high spatial and temporal precision across large areas of the brain. Advanced innovations in designing high-density neural interfaces for small animal models have enabled breakthrough discoveries in neuroscience research. Developing similar neurotechnology for larger animal models such as nonhuman primates (NHPs) is critical to gain significant insights for translation to humans, yet still it remains elusive due to the challenges in design, fabrication, and system-level integration of such devices. This review focuses on implantable surface neural interfaces with electrical and optical functionalities with emphasis on the required technological features to realize scalable multimodal and chronically stable implants to address the unique challenges associated with nonhuman primate studies.

Indexed as

NeuroscienceOptoelectronics

Identifiers

PMID36647381
PMCPMC9840154
OpenAlexW4312221362

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.