Evidence map›Paper›PMID 36647108›Full record

ArticleBMC medicine2023

Real-time forecasting the trajectory of monkeypox outbreaks at the national and global levels, July-October 2022.

Amanda Bleichrodt, Sushma Dahal, Kevin Maloney, Lisa Casanova, Ruiyan Luo, Gerardo Chowell

Open access · goldAbstract read
In one paragraph

Article in BMC medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
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  3. Risk perception and mpox vaccine acceptability among people living with HIV in northern Nigeria.Transactions of the Royal Society of Tropical Medicine and Hygiene · 2025
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  7. The Future of HIV: Challenges in meeting the 2030medRxiv : the preprint server for health sciences · 2025
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  12. Infectious Disease Modelling · 2024
    Article
  13. Stabilizing the return to normal behavior in an epidemic.medRxiv : the preprint server for health sciences · 2023
    Article
  14. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Amanda Bleichrodt *Department of Population Health Sciences, School of Public Health, Georgia State University, Atlanta, GA, USA.
Sushma Dahal *Department of Population Health Sciences, School of Public Health, Georgia State University, Atlanta, GA, USA.
Kevin MaloneyDepartment of Population Health Sciences, School of Public Health, Georgia State University, Atlanta, GA, USA.
Lisa CasanovaDepartment of Population Health Sciences, School of Public Health, Georgia State University, Atlanta, GA, USA.
Ruiyan LuoDepartment of Population Health Sciences, School of Public Health, Georgia State University, Atlanta, GA, USA.
Gerardo ChowellDepartment of Population Health Sciences, School of Public Health, Georgia State University, Atlanta, GA, USA. gchowell@gsu.edu.
Georgia State University · US

Funding

Ebola modeling: behavior, asymptomatic infection, and contacts (2019-nCoV Admin Supplement)R01GM130900 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI PORCO, TRAVIS CHRISTIAN · 2019 to 2022
$1.6M
National Science Foundation 1610429National Science Foundation 1633381NIGMS NIH HHS R01 GM130900
6 · The paper itself

Abstract

backgroundBeginning May 7, 2022, multiple nations reported an unprecedented surge in monkeypox cases. Unlike past outbreaks, differences in affected populations, transmission mode, and clinical characteristics have been noted. With the existing uncertainties of the outbreak, real-time short-term forecasting can guide and evaluate the effectiveness of public health measures.

methodsWe obtained publicly available data on confirmed weekly cases of monkeypox at the global level and for seven countries (with the highest burden of disease at the time this study was initiated) from the Our World in Data (OWID) GitHub repository and CDC website. We generated short-term forecasts of new cases of monkeypox across the study areas using an ensemble n-sub-epidemic modeling framework based on weekly cases using 10-week calibration periods. We report and assess the weekly forecasts with quantified uncertainty from the top-ranked, second-ranked, and ensemble sub-epidemic models. Overall, we conducted 324 weekly sequential 4-week ahead forecasts across the models from the week of July 28th, 2022, to the week of October 13th, 2022.

resultsThe last 10 of 12 forecasting periods (starting the week of August 11th, 2022) show either a plateauing or declining trend of monkeypox cases for all models and areas of study. According to our latest 4-week ahead forecast from the top-ranked model, a total of 6232 (95% PI 487.8, 12,468.0) cases could be added globally from the week of 10/20/2022 to the week of 11/10/2022. At the country level, the top-ranked model predicts that the USA will report the highest cumulative number of new cases for the 4-week forecasts (median based on OWID data: 1806 (95% PI 0.0, 5544.5)). The top-ranked and weighted ensemble models outperformed all other models in short-term forecasts.

conclusionsOur top-ranked model consistently predicted a decreasing trend in monkeypox cases on the global and country-specific scale during the last ten sequential forecasting periods. Our findings reflect the potential impact of increased immunity, and behavioral modification among high-risk populations.

Indexed as

EpidemicsMpox, MonkeypoxDisease OutbreaksForecastingHumansPublic HealthCountry levelEnsemble modelGlobalMathematical modelMonkeypoxReal-time forecastsSub-epidemic

Identifiers

PMID36647108
PMCPMC9841951
OpenAlexW4316494520

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.