Evidence map›Paper›PMID 36647053›Full record

ArticleBMC cancer2023

Carboxylated superparamagnetic Fe

Changyuan Wang, Yang Wang, Wangchuan Xiao, Xiaohua Chen, Renfu Li, Zhiyong Shen, Fengchun Lu

Open access · goldAbstract read
In one paragraph

Article in BMC cancer, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Changyuan Wang *Department of Pediatric Surgery, Fujian Medical University Union Hospital, No. 29 Xinquan Road, 350001, Fuzhou, Fujian, China.
Yang Wang *Department of Pediatric Surgery, Fujian Medical University Union Hospital, No. 29 Xinquan Road, 350001, Fuzhou, Fujian, China.
Wangchuan XiaoDepartment of Pediatric Surgery, Fujian Medical University Union Hospital, No. 29 Xinquan Road, 350001, Fuzhou, Fujian, China.
Xiaohua ChenDepartment of Pediatric Surgery, Fujian Medical University Union Hospital, No. 29 Xinquan Road, 350001, Fuzhou, Fujian, China.
Renfu LiDepartment of Pediatric Surgery, Fujian Medical University Union Hospital, No. 29 Xinquan Road, 350001, Fuzhou, Fujian, China.
Zhiyong ShenDepartment of Pediatric Surgery, Fujian Medical University Union Hospital, No. 29 Xinquan Road, 350001, Fuzhou, Fujian, China. szy506509@fjmu.edu.cn.
Fengchun LuDepartment of Pancreatic Surgery, Fujian Medical University Union Hospital, No. 29 Xinquan Road, 350001, Fuzhou, Fujian, China. fengchun160@163.com.
Union Hospital · CNFujian Medical University · CNSanming University · CN

Funding

Joint Funds for the innovation of science and Technology 2018Y9003Natural Science Foundation of Fujian Province 2018J01305
6 · The paper itself

Abstract

backgroundUltrasmall superparamagnetic iron oxide (USPIO) nanoparticles are of potential magnetic resonance imaging (MRI) contrast agents for tumor diagnosis. However, ultrasmall particle size or negative surface charge lead to relative short half-life which limit the utilization of USPIO for in vivo MRI contrast agents.

methodsSuperparamagnetic Fe

resultsThe synthetized nanoparticles were irregular spherical, with small particle size, few agglomeration, and good dispersion in water. After modification, the potential fluctuation of nanoparticles was small, and the isoelectric point of nanoparticles changed to high pH. After 3-amino propanol modification, the weight loss of the curve from 820 to 940 °C was attributed to the decomposition of 3-amino propanol molecules on the surface. The T1 relaxation rate of nanoparticles changed little before and after modification, which proved that the modification didn't change the relaxation time. Brighter vascular images were observed after 3-amino propanol modification through measurement of magnetic resonance tumor imaging.

conclusionThese data indicated the Fe

Indexed as

Magnetite NanoparticlesNeoplasms1-PropanolAnimalsContrast MediaMagnetic Resonance ImagingMagnetic Resonance SpectroscopyPropanols1-PropanolContrast MediaMagnetite NanoparticlesPropanols3-amino propanolFe3O4Magnetic resonance imagingNanoparticlesTumor

Identifiers

PMID36647053
PMCPMC9841710
OpenAlexW4316465041

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.