Evidence map›Paper›PMID 36646651›Full record

ArticleNeurological research2023

Association of inpatient rehabilitation with functional outcome in patients with stroke receiving mechanical thrombectomy.

Chen Lin, Andrea Arevalo, Hely D Nanavati

Abstract read
In one paragraph

Article in Neurological research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Chen LinDepartment of Neurology, University of Alabama, Birmingham, United States.
Andrea ArevaloDepartment of Neurology, University of Alabama, Birmingham, United States.
Hely D NanavatiDepartment of Epidemiology, University of Alabama, Birmingham, United States.ORCID 0000-0002-4092-3067

Funding

National Dissemination of I-Corps@NCATS: Accelerating Translation through CommercializationUL1TR003096 · NCATS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI GUTIERREZ, ORLANDO M, KIMBERLY, ROBERT P. · 2019 to 2023
$43.6M
Feasibility of combination exercise and neuromodulation rehabilitation to improve post-stroke chronic painI21RX003612 · VA · BIRMINGHAM VA MEDICAL CENTER · PI LIN, CHEN · 2021 to 2023
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A randomized placebo-controlled trial of methylphenidate in Veterans with a diagnosis of post traumatic stress disorder and recent cerebral stroke.IK2CX002104 · VA · BIRMINGHAM VA MEDICAL CENTER · PI LIN, CHEN · 2021 to 2025
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CSRD VA IK2 CX002104NCATS NIH HHS UL1 TR003096RRD VA I21 RX003612
6 · The paper itself

Abstract

introductionPatients with ischemic strokes that have undergone mechanical thrombectomy (MT) can still have poor functional outcomes. Limited research exists on factors that impact functional outcomes in these patients who are discharged to inpatient rehabilitation. We examined patient characteristics correlated with 90-day outcomes in ischemic stroke patients having undergone MT and undergo acute rehabilitation.

methodsThis is a retrospective study of patients (≥18 years) who were consecutively admitted to inpatient rehabilitation after undergoing MT following an ischemic stroke event from 2015 through 2018. Functional outcomes at 90-days were determined by the modified Rankin Score (mRS). Binary logistic regression models were used to measure the association of meaningful Functional Independence Measure (FIM) change with poor-outcome (mRS >2).

resultsOut of 56 stroke patients undergoing MT, 36 had poor outcome (mRS >2) at 90-days. One unit increase in discharge FIM significantly decreased the likelihood of poor outcome by 4% [aOR = 0.96; 95% CI = 95% CI = 0.92, 0.99]. Admission FIM [aOR = 0.95; 95% CI = 0.90, 1.00] and change in FIM [aOR = 0.97; 95% CI = 0.93, 1.02] were not significantly associated poor outcome in the adjusted models.

conclusionPatients with ischemic stroke who received MT who have a worse disability, particularly at discharge, while undergoing inpatient rehabilitation have higher odds of having poor future functional outcomes. This was regardless of age, sex, or race. Future research is needed to understand the mechanisms that can improve functional performance in our patient population at the IRF.

Indexed as

Ischemic StrokeStrokeStroke RehabilitationHumansInpatientsRecovery of FunctionRetrospective StudiesThrombectomyTreatment Outcomeacute inpatient rehabilitationendovascular therapyfunctional outcomesischemic strokeMechanical thrombectomy

Identifiers

PMID36646651
PMCPMC10164039

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.