Evidence map›Paper›PMID 36645097›Full record

ArticleEuropean psychiatry : the journal of the Association of European Psychiatrists2023

Somatic comorbidities of mental disorders in pregnancy.

Vahe Khachadourian, Arad Kodesh, Stephen Z Levine, Emma Lin, Joseph D Buxbaum, Veerle Bergink, Sven Sandin, Abraham Reichenberg, Magdalena Janecka

Abstract read
In one paragraph

Article in European psychiatry : the journal of the Association of European Psychiatrists, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Genetic confounding in the associations between maternal health and autism.medRxiv : the preprint server for health sciences · 2026
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Vahe KhachadourianDepartment of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York10029, USA.ORCID 0000-0002-9882-8118
Arad KodeshThe School of Public Health, University of Haifa, Haifa, Israel.
Stephen Z LevineThe School of Public Health, University of Haifa, Haifa, Israel.ORCID 0000-0002-5544-0420
Emma LinDepartment of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York10029, USA.
Joseph D BuxbaumDepartment of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York10029, USA.
Veerle BerginkDepartment of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York10029, USA.
Sven SandinDepartment of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York10029, USA.ORCID 0000-0001-6994-4884
Abraham ReichenbergDepartment of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York10029, USA.ORCID 0000-0003-2729-8575
Magdalena JaneckaDepartment of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York10029, USA.ORCID 0000-0001-7406-0776

Funding

Prenatal medication exposure in autism, birth complications and developmental disabilitiesR01HD107528 · NICHD · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI MAGDALENA JANECKA, ABRAHAM REICHENBERG · 2022 to 2026
$3.4M
Maternal health in pregnancy and autism risk - genetic and non-genetic mechanisms - Administrative SupplementR01MH124817 · NIMH · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI JANECKA, MAGDALENA · 2021 to 2025
$3.0M
Training the next generation of clinical neuroscientistsT32MH122394 · NIMH · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Rene S. Kahn, ANTONIA S NEW · 2020 to 2026
$2.5M
NIMH NIH HHS R01 MH124817NIMH NIH HHS T32 MH122394
6 · The paper itself

Abstract

backgroundMental and physical health conditions are frequently comorbid. Despite the widespread physiological and behavioral changes during pregnancy, the pattern of comorbidities among women in pregnancy is not well studied. This study aimed to systematically examine the associations between mental and somatic disorders before and during pregnancy.

methodThe study used data from mothers of a nationally representative birth cohort of children born in Israel (1997-2008). We compared the risk of all major somatic disorders (International Classification of Diseases, Ninth Revision) in pregnant women with and without a mental disorder. All analyses were adjusted for maternal age, child's birth year, family socioeconomic status, and the total number of maternal encounters with health services around pregnancy period.

resultsThe analytical sample included 77,030 mother-child dyads, with 30,083 unique mothers. The mean age at child's birth was 29.8 years. Prevalence of diagnosis of mental disorder around pregnancy in our sample was 4.4%. Comorbidity between mental and somatic disorders was two times higher than the comorbidity between pairs of different somatic disorders. Of the 17 somatic disorder categories, seven were positively associated with mental health disorders. The highly prevalent comorbidities associated with mental disorders in pregnancy included e.g. musculoskeletal (OR = 1.30; 95% CI = 1.20-1.42) and digestive system diseases (OR = 1.23; 95% CI = 1.13-1.34).

conclusionsWe observed that associations between maternal diagnoses and mental health stand out from the general pattern of comorbidity between nonmental health diseases. The study results confirm the need for screening for mental disorders during pregnancy and for potential comorbid conditions associated with mental disorders.

Indexed as

Mental DisordersAdultComorbidityFemaleHumansMaternal AgeMental HealthMothersPregnancyComorbiditymaternal healthmental disorderspregnancypsychiatric epidemiologysomatic disorders

Identifiers

PMID36645097
PMCPMC9970155

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.