ArticleJournal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine2023
The association between sleep characteristics and the risk of all-cause mortality among individuals with cardiometabolic multimorbidity: a prospective study of UK Biobank.
Article in Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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7 citing papers in PubMed.
- Association Between Sleep Patterns and the Risk of Cardiometabolic Diseases or Cardiometabolic Multimorbidity and the Mediating Role of Metabolic Biomarkers: A Prospective Study of the UK Biobank Cohort.Healthcare (Basel, Switzerland) · 2026Article
- Impact of obstructive sleep apnea and comorbid insomnia on all-cause mortality: a prospective cohort study of 2401 patients with 6-year follow-up.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2026Article
- [Joint predictive effect of systolic blood pressure variability and sleep patterns on stroke].Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2026Article
- The trajectories of cardiometabolic multimorbidity associate with mortality risk: a study based on Guangdong adult chronic diseases and risk factors cohort.Frontiers in public health · 2026Article
- Sleep Quality and Outcomes in Preclinical Heart Failure: A Prospective UK Biobank Cohort Study.The American journal of medicine · 2025Article
- The Role of Nutrition and Other Lifestyle Patterns in Mortality Risk in Older Adults with Multimorbidity.Nutrients · 2025Article
- Cardiometabolic multimorbidity, peripheral biomarkers, and dementia in rural older adults: The MIND-China study.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024Article
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4 authors.
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Abstract
STUDY
objectivesTo investigate the implications of both sleep factors and sleep patterns on the prognosis of cardiometabolic multimorbidity.
methodsFrom UK Biobank, individuals with cardiometabolic multimorbidity , defined as the coincidence of at least 2 cardiometabolic diseases (hypertension, diabetes mellitus, coronary heart disease, and stroke) were included in this study. Four low-risk sleep factors, including early chronotype, sleep 7-8 h/d, free of insomnia, and no frequent excessive daytime sleepiness, were used to generate a healthy sleep score ranging from 0 to 4. Participants with a score of 0-1, 2, 3-4 were clustered into groups with poor, intermediate, and healthy sleep pattern, respectively. We assessed the adjusted hazard ratios and 95% confidence intervals for all-cause mortality using the Cox proportional hazards model.
resultsAmong included 35,757 participants, the mean age (standard deviation)) was 61.82 (6.3) years. After full adjustment, early chronotype, sleep 7-8 h/d, no frequent excessive daytime sleepiness, and free of insomnia were independently associated with 8%, 12%, 11%, and 8% lower risk of all-cause mortality among all persons with cardiometabolic multimorbidity. We found the fully adjusted hazard ratio (95% confidence interval) for all-cause mortality was 0.90 (0.88-0.92) for a 1-point increase in the healthy sleep score. Compared with the reference group, participants with the intermediate and healthy sleep pattern had 9% and 23% lower risk of all-cause death, respectively, in the fully adjusted model.
conclusionsA healthy sleep pattern combining 4 low-risk sleep factors could be regarded as a healthy lifestyle for individuals with cardiometabolic multimorbidity to lower the risk of all-cause mortality. CITATION: He L, Ma T, Cheng X, Bai Y. The association between sleep characteristics and the risk of all-cause mortality among individuals with cardiometabolic multimorbidity: a prospective study of UK Biobank.
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