Evidence map›Paper›PMID 36644668›Full record

ArticleAtherosclerosis plus2021

Breakfast partly restores the anti-inflammatory function of high-density lipoproteins from patients with type 2 diabetes mellitus.

R F H Lemmers, N E M A Martens, A H Maas, L C van Vark-van der Zee, F P J Leijten, C M Groot-van Ruijven, M van Hoek, A G Lieverse, E J G Sijbrands, H R Haak and 4 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Atherosclerosis plus, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

R F H LemmersDepartment of Internal Medicine, Section Pharmacology and Vascular Medicine, Erasmus University Medical Center, Rotterdam, the Netherlands.
N E M A MartensDepartment of Internal Medicine, Section Pharmacology and Vascular Medicine, Erasmus University Medical Center, Rotterdam, the Netherlands.
A H MaasMáxima Medical Center, Internal Medicine, Eindhoven, the Netherlands.
L C van Vark-van der ZeeDepartment of Internal Medicine, Section Pharmacology and Vascular Medicine, Erasmus University Medical Center, Rotterdam, the Netherlands.
F P J LeijtenDepartment of Internal Medicine, Section Pharmacology and Vascular Medicine, Erasmus University Medical Center, Rotterdam, the Netherlands.
C M Groot-van RuijvenDepartment of Immunology, Erasmus University Medical Center, Rotterdam, the Netherlands.
M van HoekDepartment of Internal Medicine, Section Pharmacology and Vascular Medicine, Erasmus University Medical Center, Rotterdam, the Netherlands.
A G LieverseMáxima Medical Center, Internal Medicine, Eindhoven, the Netherlands.
E J G SijbrandsDepartment of Internal Medicine, Section Pharmacology and Vascular Medicine, Erasmus University Medical Center, Rotterdam, the Netherlands.
H R HaakMáxima Medical Center, Internal Medicine, Eindhoven, the Netherlands.
P J M LeenenDepartment of Immunology, Erasmus University Medical Center, Rotterdam, the Netherlands.
A J M VerhoevenDepartment of Internal Medicine, Section Pharmacology and Vascular Medicine, Erasmus University Medical Center, Rotterdam, the Netherlands.
W A DikDepartment of Immunology, Erasmus University Medical Center, Rotterdam, the Netherlands.
M T MulderDepartment of Internal Medicine, Section Pharmacology and Vascular Medicine, Erasmus University Medical Center, Rotterdam, the Netherlands.
Erasmus MC · NLRadboud University Nijmegen · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and aims: High-density lipoproteins (HDL) of patients with type 2 diabetes mellitus (T2DM) have impaired anti-inflammatory activities. The anti-inflammatory activity of HDL has been determined Methods: Blood was collected from healthy controls and T2DM patients after an overnight fast, and from T2DM patients 3 h after breakfast ( Results: HDL isolated by the three different methods from healthy controls inhibited TNFα-induced VCAM-1 expression in HCAEC. With apoA-I at 0.7 μM, HDL Conclusions: The

Indexed as

BreakfastDensity gradient centrifugationEndotheliumHigh-density lipoprotein functionType 2 diabetes mellitusVCAM-1

Identifiers

PMID36644668
PMCPMC9833245
OpenAlexW3194811865

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.