ArticleCase reports in pathology2023
Mixed Epithelial and Stromal Tumor: A Rare Renal Neoplasm-Case Report with Clinicopathologic Features and Review of the Literature.
Article in Case reports in pathology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 9 citations in OpenAlex.
- Hyperattenuation on non-enhanced CT and T2 hypointensity: an imaging pattern frequently associated with fibrous or smooth muscle-rich abdominal and pelvic lesions.Abdominal radiology (New York) · 2026Review
- Role of imaging in the diagnosis and management of mixed epithelial and stromal tumors of the kidney: Case series and comprehensive review.Radiology case reports · 2025Article
- Mixed Epithelial and Stromal Tumor of the Kidney: Clinicopathologic Features and Surgical Outcomes in Four Patients.Cureus · 2025Article
- Case Report: Clinical and pathological features of a metastasizing malignant mixed epithelial and stromal tumor of the kidney in a Siberian tiger (Frontiers in veterinary science · 2025Article
- Myopericytoma/myofibroma as a stromal component of mixed epithelial and stromal tumor of the kidney: A case report.Experimental and therapeutic medicine · 2024Article
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- Is it possible to diagnose mixed epithelial and stromal tumor of kidney prior to surgery? A case report.SAGE open medical case reports · 2024Article
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mixed epithelial and stromal tumor (MEST) is a rare benign renal neoplasm composed of epithelial and stromal components. Here, we report a 61-year-old woman presenting with a left complex cystic renal mass. The lesion was found incidentally on ultrasound for abdominal discomfort. CT scan and MRI showed a 7.4 cm complex cystic lesion in the left kidney. The differential diagnoses included complex renal cyst and cystic renal cell carcinoma. Laparoscopic nephrectomy showed a large 7.5 cm multicystic tumor with thick and thin septae and smooth walled-cysts containing clear watery fluid. Histologic examination showed variable sized cysts lined by flattened, cuboidal to columnar epithelium with focal hobnailing. No significant cytologic atypia or mitoses were noted. The cyst lining epithelium was positive for CK7 and high molecular weight cytokeratin (34Be12). The stroma was positive for alpha smooth muscle actin, CD10, estrogen receptor, and progesterone receptor. This report contributes an additional case to our collective knowledge of these lesions and summarizes the literature around these rare neoplasms.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.