Evidence map›Paper›PMID 36644379›Full record

ArticleJournal of ginseng research2023

Polysaccharides from

Huibin Zhu, Jianhong Cao, Xinyi Liang, Meng Luo, Anrong Wang, Ling Hu, Ruliu Li

Open access · goldAbstract read
In one paragraph

Article in Journal of ginseng research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Huibin ZhuPi-wei Institute, Science and Technology Innovation Center, Guangzhou University of Chinese Medicine, Guangzhou, China.
Jianhong CaoPi-wei Institute, Science and Technology Innovation Center, Guangzhou University of Chinese Medicine, Guangzhou, China.
Xinyi LiangPi-wei Institute, Science and Technology Innovation Center, Guangzhou University of Chinese Medicine, Guangzhou, China.
Meng LuoPi-wei Institute, Science and Technology Innovation Center, Guangzhou University of Chinese Medicine, Guangzhou, China.
Anrong WangPi-wei Institute, Science and Technology Innovation Center, Guangzhou University of Chinese Medicine, Guangzhou, China.
Ling HuPi-wei Institute, Science and Technology Innovation Center, Guangzhou University of Chinese Medicine, Guangzhou, China.
Ruliu LiPi-wei Institute, Science and Technology Innovation Center, Guangzhou University of Chinese Medicine, Guangzhou, China.
Guangzhou University of Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and aim: Methods: Rat model of intestinal mucosal injury was induced by indomethacin. The fractional cell migration was carried out by immunohistochemistry staining with BrdU. The morphological observations on intestinal mucosal injury were also performed. Intestinal epithelial cell (IEC-6) migration in vitro was conducted by scratch method. Western-blot was adopted to determine the expressions of PLC-γ1, Rac1, TRPC1, RhoA and Cav-1. Immunoprecipitation was used to evaluate the levels of Rac1/PLC-γ1, RhoA/TRPC1 and Cav-1/TRPC1. Results: The results showed that PGP effectively reduced the assessment of intestinal mucosal injury, reversed the inhibition of epithelial cell migration induced by Indomethacin, and increased the level of Ca Conclusion: PGP increases the Ca

Indexed as

BrdU, 5-bromo-2'-deoxyuridineCa2+[Ca2+]cyt, Cytosolic free Ca2+Cav-1, Caveolin-1CCE, CapacitativeCa2+ entryCell migrationER, Endoplasmic reticulumHPGPC, High-performance gel permeation chromatographyIEC-6IEC-6, Intestinal epithelial cellIntestinal mucosal injuryIP3, Inositol (1,4,5)-tresphospatePanax ginseng polysaccharidesPGP, Polysaccharides from Panax ginsengPLC-γ1, Phospholipase C-γ1Put, PutrescineSOCs, Store-operated Ca2+channelsTCM, Traditional Chinese MedicineTRPC1, Canonical transient receptor potential-1

Identifiers

PMID36644379
PMCPMC9834020
OpenAlexW4281684284

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.