ArticleEnvironmental advances2022
Maternal fluoride exposure, fertility and birth outcomes: The MIREC cohort.
Article in Environmental advances, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed, 22 citations in OpenAlex.
- Prenatal fluoride exposure and pregnancy outcomes in two US pregnancy cohorts.International journal of epidemiology · 2026Article
- Protective versus risky: the complex relationship between prenatal fluoride exposure and birth outcomes in a Chinese large-scale population study.Environmental health : a global access science source · 2026Article
- Community Water Fluoridation and Birth Outcomes.JAMA network open · 2026Article
- Assessing Fluoride Concentrations in Iowa's Groundwater and Drinking Water: Implications for Public Health and Water Management.Environmental science. Advances · 2026Article
- Water Fluoridation and Birth Outcomes in California.Environmental health perspectives · 2024Article
- Regional and racial/ethnic inequalities in public drinking water fluoride concentrations across the US.Journal of exposure science & environmental epidemiology · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 4 institutions in 2 countries.
Funding
Abstract
Objective: Fluoride exposure >1.5 mg/L from water has been associated with adverse pregnancy and birth outcomes. Little is known, however, about the effect of fluoride at levels consistent with water fluoridation (i.e., 0.7 mg/L) on pregnancy and birth outcomes. We examined the relationship between maternal fluoride exposure, fertility, and birth outcomes in a Canadian pregnancy cohort living in areas where municipal drinking water fluoride concentrations ranged from 0.04 to 0.87 mg/L. Methods: Using data from the Maternal-Infant Research on Environmental Chemicals (MIREC) study, we estimated fluoride exposure during pregnancy using three different metrics: (1) maternal urinary fluoride concentrations standardized for specific gravity (MUF Results: Median (IQR) MUF Conclusion: Fluoride exposure during pregnancy was not associated with fertility or birth outcomes in this Canadian cohort.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.