Evidence map›Paper›PMID 36644281›Full record

ArticleJACC. Basic to translational science2022

A Novel Puncturable Atrial Septal Defect Occluder: The Results of Preclinical Experiment and First-in-Human Study.

Xiaochun Zhang, Shasha Chen, Wei Li, Hasan Jilaihawi, Kerstin Piayda, Horst Sievert, Daxin Zhou, Wenzhi Pan, Junbo Ge

Abstract read
In one paragraph

Article in JACC. Basic to translational science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Article
  4. Experimental Study of the TAI QINGActa Cardiologica Sinica · 2025
    Article
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Xiaochun ZhangDepartment of Cardiology, Shanghai Institute of Cardiovascular Disease, Zhongshan Hospital, Fudan University, National Clinical Research Center for Interventional Medicine, Shanghai, China.
Shasha ChenDepartment of Cardiology, Shanghai Institute of Cardiovascular Disease, Zhongshan Hospital, Fudan University, National Clinical Research Center for Interventional Medicine, Shanghai, China.
Wei LiDepartment of Echocardiography, Shanghai Institute of Cardiovascular Disease, Zhongshan Hospital, Fudan University, Shanghai, China.
Hasan JilaihawiNYU Langone Health, New York, New York, USA.
Kerstin PiaydaCardiovascular Center Frankfurt, Frankfurt, Germany.
Horst SievertCardiovascular Center Frankfurt, Frankfurt, Germany.
Daxin ZhouDepartment of Cardiology, Shanghai Institute of Cardiovascular Disease, Zhongshan Hospital, Fudan University, National Clinical Research Center for Interventional Medicine, Shanghai, China.
Wenzhi PanDepartment of Cardiology, Shanghai Institute of Cardiovascular Disease, Zhongshan Hospital, Fudan University, National Clinical Research Center for Interventional Medicine, Shanghai, China.
Junbo GeDepartment of Cardiology, Shanghai Institute of Cardiovascular Disease, Zhongshan Hospital, Fudan University, National Clinical Research Center for Interventional Medicine, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

ReAces is a novel puncturable transcatheter atrial septal defect occluder. The device success rate was 100% (n = 14 of 14) in the animal experiment. Four swine successfully received puncture of the device 60 days after implantation of the device. The acute procedure success rate in the 10 patients was 100%. Transthoracic echocardiography examination showed that the devices were well positioned with no residual shunt, and the area of central portion of occluder was substantially thin. It is safe and effective to use ReAces for closure of secundum atrial septal defect, and puncture the atrial septum at the portion of the device is feasible.

Indexed as

AF, atrial fibrillationASD, atrial septal defectatrial septal defectatrial septal punctureCTA, computed tomography angiographyICE, intracardiac echocardiographyoccluderPET, polyethylene terephthalatetranscatheter closureTTE, transthoracic echocardiography

Identifiers

PMID36644281
PMCPMC9831856

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.