Evidence map›Paper›PMID 36644220›Full record

ArticleDrug and alcohol dependence reports2022

Time-lagged association between counseling and/or 12-Step attendance with subsequent opioid use in a secondary analysis from a randomized, clinical trial of medications for opioid use disorder.

Kathryn Hefner, Tse-Hwei Choo, Dikla Shmueli-Blumberg, Martina Pavlicova, Jacquie King, Marc Fishman, Matisyahu Shulman, Aimee Campbell, Miranda Greiner, Jennifer Scodes and 4 more

Abstract read
In one paragraph

Article in Drug and alcohol dependence reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Kathryn HefnerNIDA Data and Statistics Center for the NIDA CTN, The Emmes Company, LLC, 401 N Washington St, Rockville, MD 20850, United States.
Tse-Hwei ChooDepartment of Psychiatry, Columbia University, United States.
Dikla Shmueli-BlumbergNIDA Data and Statistics Center for the NIDA CTN, The Emmes Company, LLC, 401 N Washington St, Rockville, MD 20850, United States.
Martina PavlicovaDepartment of Biostatistics, Mailman School of Public Health, Columbia University, United States.
Jacquie KingNIDA Data and Statistics Center for the NIDA CTN, The Emmes Company, LLC, 401 N Washington St, Rockville, MD 20850, United States.
Marc FishmanMaryland Treatment Center, United States.
Matisyahu ShulmanDepartment of Psychiatry, Columbia University, United States.
Aimee CampbellDepartment of Psychiatry, Columbia University, United States.
Miranda GreinerDepartment of Psychiatry, Columbia University, United States.
Jennifer ScodesDepartment of Psychiatry, Columbia University, United States.
Sarah Meyers-OhkiNew York University Grossman School of Medicine, United States.
Patricia NovoNew York University Grossman School of Medicine, United States.
Edward NunesDepartment of Psychiatry, Columbia University, United States.
John RotrosenNew York University Grossman School of Medicine, United States.

Funding

Project-003UG1DA013035 · NIDA · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Aimee N Campbell, Jennifer McNeely · 2015 to 2026
$130.3M
CU PARTNERS: NY/LONG ISLAND REGIONAL NODEU10DA013035 · NIDA · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI NUNES, EDWARD V., ROTROSEN, JOHN P · 2001 to 2015
$47.6M
NIDA CLINICAL TRIALS NETWORK - NYC EAST SIDE NODEU10DA013046 · NIDA · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI ROTROSEN, JOHN P · 2000 to 2009
$20.2M
PROCESS DEVELOPMENT OF TELACEBEC FOR TUBERCULOSIS75N95024D00012 · NIDA · MIDWEST RESEARCH INSTITUTE · PI SLADE, DESMOND · 2024 to 2025
$742k
SCIENTIFIC, OPERATIONS, AND ADMINISTRATIVE RESOURCES (SOAR) TO NIH.75N95021D00012 · NIDA · KELLY SERVICES, INC. · PI SPROSE, SARA · 2021 to 2021
$57k
NIDA NIH HHS 75N95021D00012NIDA NIH HHS 75N95024D00012NIDA NIH HHS HHSN271201400028CNIDA NIH HHS U10 DA013035NIDA NIH HHS U10 DA013046NIDA NIH HHS UG1 DA013035NIEHS NIH HHS 75N96020D00012ORFDO NIH HHS 75N99020D00012
6 · The paper itself

Abstract

Introduction: Psychosocial support is recommended in conjunction with medication for opioid use disorder (MOUD), although optimal "dose," modality, and timing of participation is not established. This study comprised a secondary analysis of counseling and 12-Step attendance and subsequent opioid use in a MOUD randomized clinical trial. Methods: The parent study randomly assigned 570 participants to receive buprenorphine-naloxone (BUP-NX, Results: Any counseling or 12-Step attendance was associated with reduced odds of opioid use at the subsequent visit, whether considered individually or aggregated across type. A continuous relationship was observed for 12-Step attendance (F(1,5083)=5.01, Conclusions: Psychosocial engagement has a proximal association with opioid use, the strength of that association may grow with dose and time. Alternatively, more motivated individuals may both attend more counseling/12-Step and have better treatment outcomes, or the relationship may be reciprocal.

Indexed as

12-StepMedication for opioid use disorder (MOUD)Opioid use disorderPsychosocial counseling

Identifiers

PMID36644220
PMCPMC9838184

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.