Evidence map›Paper›PMID 36644200›Full record

ArticleAtherosclerosis plus2022

Circular RNA expression profile of H

Can Hou, Yong Wang, Yanjun Wang, Yaqing Zhou, Lei Hua, Jiaxin Chen, Shu He, Sheng Zhang, Enzhi Jia

Open access · goldAbstract read
In one paragraph

Article in Atherosclerosis plus, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Can HouDepartment of Cardiovascular Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, Jiangsu Province, China.
Yong WangDepartment of Cardiovascular Medicine, Nanjing Gaochun People's Hospital, Nanjing, 210029, Jiangsu Province, China.
Yanjun WangDepartment of Cardiovascular Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, Jiangsu Province, China.
Yaqing ZhouDepartment of Cardiovascular Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, Jiangsu Province, China.
Lei HuaDepartment of Cardiovascular Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, Jiangsu Province, China.
Jiaxin ChenDepartment of Cardiovascular Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, Jiangsu Province, China.
Shu HeDepartment of Cardiovascular Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, Jiangsu Province, China.
Sheng ZhangDepartment of Cardiovascular Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, Jiangsu Province, China.
Enzhi JiaDepartment of Cardiovascular Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, Jiangsu Province, China.
Jiangsu Province Hospital · CNGaochun People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and aims: Coronary artery disease (CAD) is among the most common type of cardiovascular diseases. The role of circular RNAs (circRNAs) and ferroptosis in CAD remains largely unexplored. The aim of this study was to evaluate the circRNAs expression profile in ferroptosis of human coronary artery endothelial cells (HCAECs). Methods: The ferroptosis induced by H Results: LDH, MDA, Lipid ROS, ferrous ions, GSSH and PTGS2 were significantly increased, CCK8, GSH and GPX4 were significantly decreased in H Conclusions: These results provide new sight to the character of circRNAs in the progress of HCAECs ferroptosis and contribute a significant data for further investigating the potential mechanisms of CAD.

Indexed as

CircRNAsCoronary artery diseaseFerroptosis

Identifiers

PMID36644200
PMCPMC9833229
OpenAlexW4229025163

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.