Evidence map›Paper›PMID 36644146›Full record

ArticleOncology letters2023

HER2 classification in breast cancer cells: A new explainable machine learning application for immunohistochemistry.

Claudio Cordova, Roberto Muñoz, Rodrigo Olivares, Jean-Gabriel Minonzio, Carlo Lozano, Paulina Gonzalez, Ivanny Marchant, Wilfredo González-Arriagada, Pablo Olivero

Open access · diamondAbstract read
In one paragraph

Article in Oncology letters, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 26 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Claudio CordovaCell Function and Structure Laboratory (EFC Lab.), Faculty of Medicine, Universidad de Valparaíso, Valparaíso 2341386, Chile.
Roberto MuñozPhD Program in Health Sciences and Engineering, Faculty of Engineering, Universidad de Valparaíso, Valparaíso 2362735, Chile.
Rodrigo OlivaresSchool of Informatics Engineering, Faculty of Engineering, Universidad de Valparaíso, Valparaíso 2362735, Chile.
Jean-Gabriel MinonzioPhD Program in Health Sciences and Engineering, Faculty of Engineering, Universidad de Valparaíso, Valparaíso 2362735, Chile.
Carlo LozanoPathological Anatomy Service, Carlos Van Buren Hospital, Valparaíso 2340105, Chile.
Paulina GonzalezPathological Anatomy Service, Carlos Van Buren Hospital, Valparaíso 2340105, Chile.
Ivanny MarchantMedical Modeling Laboratory, Faculty of Medicine, Universidad de Valparaíso, Valparaíso 2362735, Chile.
Wilfredo González-ArriagadaFaculty of Dentistry, Universidad de los Andes, Santiago 7620086, Chile.
Pablo OliveroCell Function and Structure Laboratory (EFC Lab.), Faculty of Medicine, Universidad de Valparaíso, Valparaíso 2341386, Chile.
University of Valparaíso · CLHospital Carlos Van Buren · CLUniversidad de Los Andes, Chile · CL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The immunohistochemical (IHC) evaluation of epidermal growth factor 2 (HER2) for the diagnosis of breast cancer is still qualitative with a high degree of inter-observer variability, and thus requires the incorporation of complementary techniques such as fluorescent

Indexed as

breast cancerHER2IHCMLSHAP

Identifiers

PMID36644146
PMCPMC9811637
OpenAlexW4311401918

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.