ArticleCureus2022
Eleven-Year Trend of Drug and Chemical Substance Overdose at a Local Emergency Hospital in Japan.
Article in Cureus, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 13 citations in OpenAlex.
- Association between adverse childhood experiences and over-the-counter drug abuse in Japan: A nationwide population-based cross-sectional study.PCN reports : psychiatry and clinical neurosciences · 2026Article
- Clinical characteristics of patients who attempt suicide by drug overdose in Western China: a retrospective analysis.BMC psychiatry · 2025Article
- Response to 'International trends in male youth suicide and suicidal behaviour'.Acta neuropsychiatrica · 2025Article
- Dependence, abuse, and psychosocial characteristics of patients transported to the emergency department due to overdose of over-the-counter drugs.PCN reports : psychiatry and clinical neurosciences · 2025Article
- Investigation of commercially available recombinant and conventional β-glucuronidases to evaluate the hydrolysis efficiencies against O-glucuronides and N-glucuronides in urinary drug screening.Forensic toxicology · 2025Article
- Quality Assessment of Medical Institutions' Websites Regarding Prescription Drug Misuse of Glucagon-Like Peptide-1 Receptor Agonists by Off-Label Use for Weight Loss: Website Evaluation Study.JMIR formative research · 2025Article
- Characteristics of the drinking habits of people who overdose over-the-counter drugs: Insights from a nationwide Japanese survey.PCN reports : psychiatry and clinical neurosciences · 2024Article
- Illicit Trade of Prescription Medications Through X (Formerly Twitter) in Japan: Cross-Sectional Study.JMIR formative research · 2024Article
- Clinical characteristics of over-the-counter (OTC) drug abusers in psychiatric practice in Japan: Comparison of single and multiple OTC product abusers.Neuropsychopharmacology reports · 2024Article
Corrections and comments
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Authors and funding
5 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe purpose of this study was to investigate long-term trends of overdose in the emergency department of a regional core hospital in Sendai, Miyagi Prefecture, Japan, and to identify patient characteristics as well as drugs and chemicals associated with overdose.
methodsPatients who visited the emergency department from January 1, 2010, to December 31, 2020, and were diagnosed with a drug or chemical overdose were included in the study. We conducted a descriptive analysis based on the data collected.
resultsIn total, 577 patients (mean 38.4 years old, female 75.0%) were considered, and 16.8% had a history of repeated overdose. The number of patients during the study period showed a downward trend, with slight increases in 2012 and 2020. In addition, the top four drugs suspected of causing overdose were over the counter (OTC) antipyretic analgesics and cold medicines (N=97), followed by flunitrazepam (N=80), etizolam (N=72), and brotizolam (N=70).
conclusionThere was a decreasing trend in overdose, and OTC medicines, sedatives, and anxiolytics were the primary medications causing overdose. OTC antipyretic analgesics and cold medicines were the most common suspected overdose drugs, with an increasing trend in the later years.
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