Evidence map›Paper›PMID 36643798›Full record

ArticleAtherosclerosis plus2022

Risk stratification and lipid evaluation in mexican patients, evidence of lipid and cardiovascular analysis in REMECAR. The mexican registry of cardiovascular diseases (REMECAR group).

Manuel Odín De Los Ríos-Ibarra, José Luis Leiva-Pons, Humberto Rodríguez-Reyes, Marco Antonio Alcocer-Gamba, Jorge Cortés-Lawrenz, Frida María Vizcaíno-Rios, Jaime Barragán-Luna, Julio Iván Farjat-Ruiz, Luis R Virgen-Carrillo, Francisco Padilla-Padilla and 4 more

Open access · goldAbstract read
In one paragraph

Article in Atherosclerosis plus, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 9 institutions in 2 countries.

Manuel Odín De Los Ríos-IbarraMexican Academic Consortium for Clinical Data Acquisition SC, Mexico.
José Luis Leiva-PonsMexican Academic Consortium for Clinical Data Acquisition SC, Mexico.
Humberto Rodríguez-ReyesSociedad Cardiovascular y Arritmias, Aguascalientes, Mexico.
Marco Antonio Alcocer-GambaMexican Academic Consortium for Clinical Data Acquisition SC, Mexico.
Jorge Cortés-LawrenzHermosillo Heart Team - Hospital CIMA, Hermosillo, Mexico.
Frida María Vizcaíno-RiosCentro para El Desarrollo de La Medicina y Asistencia Médica Especializada, Culiacán, Mexico.
Jaime Barragán-LunaHospital Regional PEMEX, Poza Rica, Mexico.
Julio Iván Farjat-RuizCentro Médico de Las Américas/CMFEQ12 ISSSTE, Mérida, Mexico.
Luis R Virgen-CarrilloVirgen Cardiovascular Research, Guadalajara, Mexico.
Francisco Padilla-PadillaCardiometabolic Research Center/MAC Hospital, Aguascalientes, Mexico.
Abel Pavia-LópezCentro Médico ABC, Mexico.
Enrique C Morales-VillegasCardiometabolic Research Center/MAC Hospital, Aguascalientes, Mexico.
Natalie C WardDobney Hypertension Centre, Medical School, University of Western Australia, Perth, Australia.
Leslie Marisol Lugo-GavidiaMexican Academic Consortium for Clinical Data Acquisition SC, Mexico.
Mexican Association for the Clinical Research · MXThe University of Western Australia · AUAutonomous University of Queretaro · MXCentro Médico ABC · MXHospital Central Dr. Ignacio Morones Prieto · MXInstitute for Social Security and Services for State Workers · MXPemex (Mexico) · MXUniversidad de Hermosillo · MXUniversidad Villasunción · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and aims: Dyslipidaemia is a significant risk factor for cardiovascular disease in the Mexican population. This analysis aimed to describe the baseline LDL-c levels of patients presenting to cardiovascular clinics and evaluate the proportion who achieved their risk-based LDL-c goals as recommended by 2021 ESC prevention guidelines. Methods: The REMECAR registry is an observational study of patients attending a specialized cardiovascular clinic for their first visit. The cardiovascular risk was retrospectively determined using the 2021 ESC guideline stratification and the SCORE2 and SCORE-OP. Results: A total of 5443 patients were included in the analysis. Within this population, 55.96% presented as very high, 39.98% as high and 4.06% as moderate to low risk. 63% of the participants were not on any lipid-lowering treatment at entry, while 12.4% were receiving high-intensity statin therapy. Patients presenting with established atherosclerotic cardiovascular disease had a mean LDL-c of 90.9 ± 40.7 mg/dL. Of these, 14.1% were achieving LDL-c levels of 70-55 mg/dL and 19.3% were achieving LDL-c levels <55 mg/dL. In diabetic patients at very high risk, only 25.7% achieved their LDL-c goal. Finally, in patients without another risk factor and very high-risk evaluated by SCORE2 & SCORE-OP, only 14% of patients achieved their LDL-c goals. Conclusions: An important number of patients were not receiving any lipid-lowering therapy. Furthermore, in those who were, a significant portion did not achieve LDL-c recommended thresholds. Our results underline the urgent need to improve the prescription and optimization of lipid-lowering therapy as the current management appears to be insufficient for achieving optimal recommended goals. Identifying key barriers in lipid management is fundamental to establishing better strategies and health system policies to reduce cardiovascular risk.

Indexed as

LDL-C goalREMECAR registryRisk assessment

Identifiers

PMID36643798
PMCPMC9833238
OpenAlexW4293393110

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.