Evidence map›Paper›PMID 36643677›Full record

ArticleTranslational pediatrics2022

Pathogenesis of bronchopulmonary dysplasia in preterm neonates revealed by an RNA sequencing interaction network analysis.

Fengdan Xu, Yabo Mei, Yaozhong Zhang, Qin Chen, Jinfeng Liao, Xiaoguang He, Zhichun Feng, Xingyun Wang, Ning Li

Open access · diamondAbstract read
In one paragraph

Article in Translational pediatrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 3 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Fengdan Xu *Department of Neonatology, Dongguan Children's Hospital Affiliated to Guangdong Medical University, Dongguan, China.
Yabo Mei *Department of Pediatrics, the Seventh Medical Center of PLA General Hospital, Beijing, China.
Yaozhong ZhangDongguan Institute of Pediatrics, Dongguan Children's Hospital Affiliated to Guangdong Medical University, Dongguan, China.
Qin ChenDepartment of Neonatology, Dongguan Children's Hospital Affiliated to Guangdong Medical University, Dongguan, China.
Jinfeng LiaoDepartment of Neonatology, Dongguan Children's Hospital Affiliated to Guangdong Medical University, Dongguan, China.
Xiaoguang HeDepartment of Neonatology, Dongguan Children's Hospital Affiliated to Guangdong Medical University, Dongguan, China.
Zhichun FengDepartment of Pediatrics, the Seventh Medical Center of PLA General Hospital, Beijing, China.
Xingyun WangHongqiao International Institute of Medicine, Tongren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Ning LiDepartment of Neonatology, Dongguan Children's Hospital Affiliated to Guangdong Medical University, Dongguan, China.
Dongguan People’s Hospital · CNChinese PLA General Hospital · CNGuangdong Medical College · CNTongren Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The chronic lung condition known as bronchopulmonary dysplasia (BPD), which primarily affects newborns, especially preterm neonates, is brought on by prolonged oxygen consumption and mechanical ventilation. This case-control study sought to investigate the pathogenesis of BPD in preterm neonates by RNA sequencing (RNA-seq). Methods: First, RNA-seq samples were collected from 3 BPD and 3 healthy preterm neonates. Based on the sequencing data and microarray data sets, Results: Among the 32 genes in the dark-red module and the 158 differentially expressed lncRNAs, 21 overlapping genes were identified. In the gene expression analysis, Conclusions: This study identified 1 key upregulated lncRNA (i.e.,

Indexed as

eukaryotic translation initiation factor 5A (EIF5A)hsa-miR-6833-5pMERGE.57185.1Preterm neonatal bronchopulmonary dysplasia (preterm neonatal BPD)RNA sequencing (RNA-seq)

Identifiers

PMID36643677
PMCPMC9834945
OpenAlexW4313249083

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.