Evidence map›Paper›PMID 36643587›Full record

ArticleMediators of inflammation2023

Resveratrol Improves the Progression of Osteoarthritis by Regulating the SIRT1-FoxO1 Pathway-Mediated Cholesterol Metabolism.

ChuanCai Liang, Hengte Xing, ChenYu Wang, XiongFeng Xu, Yarong Hao, Bo Qiu

Open access · goldAbstract read
In one paragraph

Article in Mediators of inflammation, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
7.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 25 citations in OpenAlex.

  1. Review
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  4. Forkhead box O proteins in chondrocyte aging and diseases.Journal of orthopaedic translation · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

ChuanCai LiangDepartment of Orthopedics, Renmin Hospital of Wuhan University, Wuhan, China.
Hengte XingDepartment of Orthopedics, Renmin Hospital of Wuhan University, Wuhan, China.
ChenYu WangDepartment of Orthopedics, Renmin Hospital of Wuhan University, Wuhan, China.
XiongFeng XuDepartment of Orthopedics, Renmin Hospital of Wuhan University, Wuhan, China.
Yarong HaoDepartment of Geriatrics, Renmin Hospital of Wuhan University, Wuhan, China.ORCID https://orcid.org/0000-0001-5831-0771
Bo QiuDepartment of Orthopedics, Renmin Hospital of Wuhan University, Wuhan, China.ORCID https://orcid.org/0000-0002-1487-3537
Wuhan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Osteoarthritis (OA) is considered a metabolic disorder. This study investigated the effect of resveratrol (RES) on cholesterol accumulation in osteoarthritic articular cartilage via the silent information regulator 1 (SIRT1)/forkhead transcription factor (FoxO1) pathway. Interleukin (IL)-1

Indexed as

Cartilage, ArticularOsteoarthritisAnimalsCells, CulturedCholesterolChondrocytesForkhead Box Protein O1Interleukin-1betaMiceResveratrolSirtuin 1CholesterolForkhead Box Protein O1Foxo1 protein, mouseInterleukin-1betaResveratrolSirt1 protein, mouseSirtuin 1

Identifiers

PMID36643587
PMCPMC9833897
OpenAlexW4313590867

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.