Evidence map›Paper›PMID 36643548›Full record

ArticleACS omega2023

Petasis Sequence Reactions for the Scaffold-Diverse Synthesis of Bioactive Polycyclic Small Molecules.

Amrutha K Avathan Veettil, Jan-Lukas Kirchhoff, Lukas Brieger, Carsten Strohmann, Peng Wu

Abstract read
In one paragraph

Article in ACS omega, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Amrutha K Avathan VeettilChemical Genomics Centre, Max Planck Institute of Molecular Physiology, Dortmund 44227, Germany.
Jan-Lukas KirchhoffFaculty of Chemistry and Chemical Biology, TU Dortmund University, Dortmund 44227, Germany.
Lukas BriegerFaculty of Chemistry and Chemical Biology, TU Dortmund University, Dortmund 44227, Germany.
Carsten StrohmannFaculty of Chemistry and Chemical Biology, TU Dortmund University, Dortmund 44227, Germany.
Peng WuChemical Genomics Centre, Max Planck Institute of Molecular Physiology, Dortmund 44227, Germany.ORCID https://orcid.org/0000-0002-0186-1086

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The multicomponent Petasis reaction is a versatile method to access functionalized amines. The combination of Petasis reaction with subsequent ring-closing reactions is a powerful strategy to build novel polycyclic scaffolds. In this study, we report the generation of a diverse set of small molecules with polycyclic scaffolds featuring a high content of sp

Identifiers

PMID36643548
PMCPMC9835185

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.