Evidence map›Paper›PMID 36643462›Full record

ReviewACS omega2023

Near-Infrared Probes for Biothiols (Cysteine, Homocysteine, and Glutathione): A Comprehensive Review.

Rahul Kaushik, Nidhi Nehra, Veronika Novakova, Petr Zimcik

Abstract readReview
In one paragraph

Review in ACS omega, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Rahul KaushikChemical Oceanography Division, CSIR National Institute of Oceanography, Dona Paula 403004, Goa, India.ORCID https://orcid.org/0000-0002-1854-1118
Nidhi NehraSchool of Chemical Sciences, Indian Association for the Cultivation of Science, 2A&2B Raja S. C. Mullick Road, Jadavpur, Kolkata 700032, India.
Veronika NovakovaDepartment of Pharmaceutical Chemistry and Pharmaceutical Analysis, Univerzita Karlova v Praze Farmaceuticka fakulta v Hradci Kralove, Akademika Heyrovského 1203, Hradec Králové 50005, Czech Republic.ORCID https://orcid.org/0000-0002-2183-1220
Petr ZimcikDepartment of Pharmaceutical Chemistry and Pharmaceutical Analysis, Univerzita Karlova v Praze Farmaceuticka fakulta v Hradci Kralove, Akademika Heyrovského 1203, Hradec Králové 50005, Czech Republic.ORCID https://orcid.org/0000-0002-3533-3601

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Biothiols (cysteine, homocysteine, and glutathione) are an important class of compounds with a free thiol group. These biothiols plays an important role in several metabolic processes in living bodies when present in optimum concentration. Researchers have developed several probes for the detection and quantification of biothiols that can absorb in UV, visible, and near-infrared (NIR) regions of the electromagnetic spectrum. Among them, NIR organic probes have attracted significant attention due to their application in in vivo and in vitro imaging. In this review, we have summarized probes for these biothiols, which could work in the NIR region, and discussed their sensing mechanism and potential applications. Along with focusing on the pros and cons of the reported probes we have classified them according to the fluorophore used and summarized their photophysical and sensing properties (emission, response time, limit of detection).

Identifiers

PMID36643462
PMCPMC9835641

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.