Evidence map›Paper›PMID 36643409›Full record

ArticleFrontiers in microbiology2022

Relationship between thick or greasy tongue-coating microbiota and tongue diagnosis in patients with primary liver cancer.

Yuren Zhang, Hetong Zhao, Yuyu Guo, Yongbin Meng, Shasha Yu, Bo Pan, Xiaofeng Zhai

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Tongue-coating microbiome as a predictor of solid tumors: an updated scoping review of clinical studies.Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan · 2026
    Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Oral microbiota disorder in GC patients revealed by 2b-RAD-M.Journal of translational medicine · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Yuren ZhangDepartment of Traditional Chinese Medicine, Changhai Hospital, Naval Military Medical University, Shanghai, China.
Hetong ZhaoDepartment of Traditional Chinese Medicine, Changhai Hospital, Naval Military Medical University, Shanghai, China.
Yuyu GuoDepartment of Traditional Chinese Medicine, Changhai Hospital, Naval Military Medical University, Shanghai, China.
Yongbin MengDepartment of Traditional Chinese Medicine, Changhai Hospital, Naval Military Medical University, Shanghai, China.
Shasha YuDepartment of Traditional Chinese Medicine, Changhai Hospital, Naval Military Medical University, Shanghai, China.
Bo PanDepartment of Traditional Chinese Medicine, Changhai Hospital, Naval Military Medical University, Shanghai, China.
Xiaofeng ZhaiDepartment of Traditional Chinese Medicine, Changhai Hospital, Naval Military Medical University, Shanghai, China.
Second Military Medical University · CNChanghai Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tongue diagnosis is a unique aspect of traditional Chinese medicine for diagnosing diseases before determining proper means of treatment, but it also has the disadvantage of relying on the subjective experience of medical practitioners and lack objective basis. The purpose of this article is to elucidate tongue-coating microbiota and metabolic differences in primary liver cancer (PLC) patients with thick or greasy tongue coatings. Tongue-coating samples were analyzed in 60 PLC patients (30 PLC with thick or greasy tongue-coating patients and 30 PLC with tongue-coating neither thick nor greasy) and 25 healthy controls (HC) using 16S rRNA gene sequencing technology. As compared to healthy individuals, tongue coatings of patients with PLC had elevated levels of

Indexed as

16S rRNA gene sequencingprimary liver cancersyndrometongue coating microbiotatraditional Chinese medicine (TCM)

Identifiers

PMID36643409
PMCPMC9835093
OpenAlexW4313327847

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.