ArticleJournal of dental sciences2023
High frequencies of vitamin B12 and folic acid deficiencies and hyperhomocysteinemia in Taiwanese male patients with oral submucous fibrosis.
Article in Journal of dental sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- Anemia, hematinic deficiencies, and hyperhomocysteinemia in younger and older oral lichen planus patients.Journal of dental sciences · 2026Article
- Higher serum gastric parietal cell antibody titers are associated with increased frequencies of macrocytosis, vitamin B12 deficiency, and hyperhomocysteinemia in patients with oral lichen planus.Journal of dental sciences · 2026Article
- Gastric parietal cell and thyroid autoantibodies in patients with oral lichen planus.Journal of dental sciences · 2026Article
- The presence of thyroid autoantibodies is not associated with anemia, hematinic deficiencies, and hyperhomocysteinemia in oral lichen planus patients.Journal of dental sciences · 2026Article
- Prevalences of vitamin B12 deficiency, pernicious anemia, macrocytosis, and hyperhomocysteinemia in 532 serum gastric parietal cell antibody-positive oral mucosal disease patients.Journal of dental sciences · 2026Article
- Biomaterial-based therapeutic strategies for oral submucous fibrosis.Frontiers in cell and developmental biology · 2026Review
- Anemia, hematinic deficiencies, hyperhomocysteinemia, and gastric parietal cell antibody positivity in oral lichen planus patients with normocytosis.Journal of dental sciences · 2025Article
- Anemia, hematinic deficiencies, and hyperhomocysteinemia in gastric parietal cell antibody-positive and -negative oral lichen planus patients.Journal of dental sciences · 2025Article
- Anemia, hematinic deficiencies, hyperhomocysteinemia, and serum gastric parietal cell antibody positivity in oral lichen planus patients with macrocytosis.Journal of dental sciences · 2025Article
- Anemia, hematinic deficiencies, hyperhomocysteinemia, and gastric parietal cell antibody positivity in oral lichen planus patients with or without microcytosis.Journal of dental sciences · 2025Article
- Anemia, hematinic deficiencies, and gastric parietal cell antibody positivity in oral lichen planus patients with or without hyperhomocysteinemia.Journal of dental sciences · 2025Article
- Anemia, hematinic deficiencies, hyperhomocysteinemia, and gastric parietal cell antibody positivity in oral lichen planus patients with iron deficiency.Journal of dental sciences · 2025Article
- Anemia, hematinic deficiencies, hyperhomocysteinemia, and serum gastric parietal cell antibody positivity in oral lichen planus patients with vitamin B12 deficiency.Journal of dental sciences · 2025Article
- Anemia, hematinic deficiencies, and hyperhomocysteinemia in male and female oral lichen planus patients.Journal of dental sciences · 2025Article
- Associations of single and multiple vitamin levels with pediatric oral mucosal diseases: a cross-sectional study with multi-model analysis.Frontiers in nutrition · 2025Article
- Anemia, hematinic deficiencies, hyperhomocysteinemia, and serum gastric parietal cell antibody positivity in 588 patients with oral lichen planus.Journal of dental sciences · 2025Article
- Higher frequencies of anemia, vitamin B12 deficiency, and gastric parietal cell antibody positivity in folic acid-deficient Taiwanese male oral submucous fibrosis patients.Journal of dental sciences · 2023Article
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Authors and funding
6 authors.
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Abstract
Background: /purpose: Oral submucous fibrosis (OSF) is a betel quid chewing-caused oral mucosal disease with progressive collagen deposition. This study evaluated whether Taiwanese male OSF patients had high frequencies of vitamin B12 and folic acid deficiencies, hyperhomocysteinemia, and serum gastric parietal cell antibody (GPCA) positivity. Materials and methods: The blood hemoglobin (Hb), serum iron, vitamin B12, folic acid, homocysteine, and GPCA concentrations in 62 male OSF patients were measured and compared with the corresponding data in 124 age-matched male healthy control subjects. Results: We found that 5 (8.1%), 12 (19.4%), 32 (51.6%), 31 (50.0%), 22 (35.5%), and 6 (9.7%) of the 62 male OSF patients had Hb (<13 g/dL), iron (≤70 μg/dL), vitamin B12 (≤450 pg/mL), and folic acid (≤6 ng/mL) deficiencies, hyperhomocysteinemia (>12 μM), and serum GPCA positivity, respectively. Furthermore, OSF patients had significantly higher frequencies of Hb ( Conclusion: We conclude that Taiwanese male OSF patients have high frequencies of vitamin B12 and folic acid deficiencies, hyperhomocysteinemia, and serum GPCA positivity. The hyperhomocysteinemia in our OSF patients is predominantly due to deficiencies of either vitamin B12 or folic acid or both.
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