Evidence map›Paper›PMID 36643052›Full record

ReviewJournal of clinical and translational hepatology2023

Seronegative Autoimmune Hepatitis.

Sriya A Bhumi, George Y Wu

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of clinical and translational hepatology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Autoantibodies in the follow-up of autoimmune hepatitis.Journal of translational autoimmunity · 2026
    Review
  5. Review
  6. Diagnostic Utility of Liver Biopsy in Persistent Unexplained Liver Enzyme Elevation: A Retrospective Cohort Study.JGH open : an open access journal of gastroenterology and hepatology · 2025
    Article
  7. Khat-associated Autoimmune Hepatitis: A Review with RUCAM Analysis.Journal of clinical and translational hepatology · 2025
    Review
  8. Article
  9. Review
  10. Article
  11. Seronegative autoimmune hepatitis in childhood.World journal of clinical pediatrics · 2023
    Review
  12. Review
  13. [Autoimmune Hepatitis: Up-to-Date Concepts].Acta gastroenterologica Latinoamericana
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Sriya A BhumiDepartment of Medicine, University of Connecticut Health Center, Farmington, CT, USA.ORCID https://orcid.org/0000-0002-6336-2119
George Y WuDepartment of Medicine, Division of Gastroenterology-Hepatology, University of Connecticut Health Center, Farmington, CT, USA.ORCID https://orcid.org/0000-0003-0068-1072

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Autoimmune hepatitis (AIH) is a relatively rare liver disease with varying worldwide incidence of from 0.7 to 2 per 100,000 people. It is characterized by the presence of auto-antibodies. However, an average of 10% of AIH cases have AIH symptoms and pathology but lack autoimmune serology. For such seronegative AIH (snAIH) cases, there is currently no established diagnostic algorithm for diagnosis. and improper or delayed diagnosis of snAIH can lead to no or inappropriate treatment that results in progression to fulminant hepatitis or cirrhosis. This review aims to review the current literature and to present an update of seronegative autoimmune hepatitis, including its pathophysiology, clinical presentation, methods of diagnosis, and treatment in order to increase awareness and emphasize the necessity for timely management.

Indexed as

Autoantibody negativeAutoimmune hepatitisCryptogenic hepatitisSeronegative autoimmune hepatitis

Identifiers

PMID36643052
PMCPMC9817061

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.