Evidence map›Paper›PMID 36642966›Full record

Trial reportLeukemia & lymphoma2023

Molecularly targeted epigenetic therapy with mocetinostat in relapsed and refractory non-Hodgkin lymphoma with

David Qualls, Ariela Noy, David Straus, Matthew Matasar, Craig Moskowitz, Venkatraman Seshan, Ahmet Dogan, Gilles Salles, Anas Younes, Andrew D Zelenetz and 1 more

Open access · hybridAbstract readClinical Trial, Phase II
In one paragraph

Trial report in Leukemia & lymphoma, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Epigenetics-targeted drugs: current paradigms and future challenges.Signal transduction and targeted therapy · 2024
    Review
  5. Review
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

David QuallsDepartment of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.ORCID 0000-0001-5297-9685
Ariela NoyDepartment of Medicine, Lymphoma Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA.ORCID 0000-0002-3001-4898
David StrausDepartment of Medicine, Lymphoma Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA.ORCID 0000-0001-8364-6816
Matthew MatasarDepartment of Medicine, Lymphoma Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA.ORCID 0000-0002-4581-3721
Craig MoskowitzDepartment of Medicine, Lymphoma Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA.ORCID 0000-0002-9189-3152
Venkatraman SeshanDepartment of Epidemiology and Biostatistics, Biostatistics Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Ahmet DoganDepartment of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.ORCID 0000-0001-6576-5256
Gilles SallesDepartment of Medicine, Lymphoma Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA.ORCID 0000-0002-9541-8666
Anas YounesDepartment of Medicine, Lymphoma Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA.ORCID 0000-0002-0001-4133
Andrew D ZelenetzDepartment of Medicine, Lymphoma Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA.ORCID 0000-0003-1403-6883
Connie Lee BatleviDepartment of Medicine, Lymphoma Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA.ORCID 0000-0002-9036-9463
Memorial Sloan Kettering Cancer Center · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
Translating Stress Response Targeted Therapy for B-Cell LymphomasP50CA192937 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI DALLA-FAVERA, RICCARDO, ZELENETZ, ANDREW D. · 2016 to 2020
$10.9M
NCI NIH HHS P30 CA008748NCI NIH HHS P50 CA192937
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Lymphoma, Non-HodgkinNeoplasm Recurrence, LocalBenzamidesCREB-Binding ProteinE1A-Associated p300 ProteinEpigenesis, GeneticHumansMutationPyrimidinesBenzamidesCREB-Binding ProteinCREBBP protein, humanE1A-Associated p300 ProteinEP300 protein, humanmocetinostatPyrimidines

Identifiers

PMID36642966
PMCPMC10841916
OpenAlexW4316368779

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.