Evidence map›Paper›PMID 36642523›Full record

ArticleInternal medicine (Tokyo, Japan)2023

Successful Treatment with Definitive Concurrent Chemoradiotherapy Followed by Durvalumab Maintenance Therapy in a Patient with Tracheal Adenoid Cystic Carcinoma.

Erika Mikami, Shinji Nakamichi, Atsuhiro Nagano, Kazuhito Misawa, Anna Hayashi, Takehiro Tozuka, Natsuki Takano, Rintaro Noro, Katsuya Maebayashi, Hirotoshi Kubokura and 3 more

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Erika MikamiDepartment of Pulmonary Medicine and Oncology, Graduate School of Medicine, Nippon Medical School, Japan.
Shinji NakamichiDepartment of Pulmonary Medicine and Oncology, Graduate School of Medicine, Nippon Medical School, Japan.
Atsuhiro NaganoDepartment of Pulmonary Medicine and Oncology, Graduate School of Medicine, Nippon Medical School, Japan.
Kazuhito MisawaDepartment of Pulmonary Medicine and Oncology, Graduate School of Medicine, Nippon Medical School, Japan.
Anna HayashiDepartment of Pulmonary Medicine and Oncology, Graduate School of Medicine, Nippon Medical School, Japan.
Takehiro TozukaDepartment of Pulmonary Medicine and Oncology, Graduate School of Medicine, Nippon Medical School, Japan.
Natsuki TakanoDepartment of Pulmonary Medicine and Oncology, Graduate School of Medicine, Nippon Medical School, Japan.
Rintaro NoroDepartment of Pulmonary Medicine and Oncology, Graduate School of Medicine, Nippon Medical School, Japan.
Katsuya MaebayashiDepartment of Radiology, Graduate School of Medicine, Nippon Medical School, Japan.
Hirotoshi KubokuraDepartment of Thoracic Surgery, Graduate School of Medicine, Nippon Medical School Musashikosugi Hospital, Japan.
Yasuhiro TerasakiDepartment of Analytic Human Pathology, Nippon Medical School, Japan.
Kaoru KubotaDepartment of Pulmonary Medicine and Oncology, Graduate School of Medicine, Nippon Medical School, Japan.
Masahiro SeikeDepartment of Pulmonary Medicine and Oncology, Graduate School of Medicine, Nippon Medical School, Japan.
Nippon Medical School · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adenoid cystic carcinoma (ACC) is a rare type of malignant tracheal tumor originating from the secretory glands. Complete surgical resection is the current standard of care for tracheal ACC. However, there have been few case reports of chemoradiotherapy for unresectable tracheal ACC. We herein report a 28-year-old man with unresectable tracheal ACC who received concurrent chemoradiotherapy (CCRT) followed by maintenance therapy with durvalumab. CCRT was completed with a good response and safety, and the patient is currently receiving durvalumab as maintenance therapy. Durvalumab after CCRT can be a treatment option for patients with unresectable tracheal ACC.

Indexed as

Carcinoma, Adenoid CysticLung NeoplasmsTracheal NeoplasmsAdultAntibodies, MonoclonalChemoradiotherapyHumansMaleTracheaAntibodies, Monoclonaldurvalumabadenoid cystic carcinomaconcurrent chemoradiotherapydurvalumabtrachea

Identifiers

PMID36642523
PMCPMC10569923
OpenAlexW4316171381

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.