Evidence map›Paper›PMID 36641434›Full record

ArticleBMC primary care2023

Effectiveness of a provider and patient-focused intervention to improve hypertension management and control in the primary health care setting in Cuba: a controlled before-after study.

Esteban Londoño Agudelo, Tullia Battaglioli, Addys Díaz Piñera, Armando Rodríguez Salvá, Tom Smekens, Fernando Achiong Estupiñán, Isabel Carbonell García, Patrick Van der Stuyft

Open access · goldAbstract read
In one paragraph

Article in BMC primary care, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Healthcare providers' perceptions of the HEARTS Clinical Pathway in Belize: barriers and facilitators.Revista panamericana de salud publica = Pan American journal of public health · 2026
    Article
  3. Article
  4. Article
  5. Review
  6. Expanding team-based care for hypertension and cardiovascular risk management with HEARTS in the Americas.Revista panamericana de salud publica = Pan American journal of public health · 2025
    Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Esteban Londoño AgudeloFacultad Nacional de Salud Pública, Grupo de Epidemiología, Universidad de Antioquia, Calle 62 #52-59, Medellín, Colombia. eaugusto.londono@udea.edu.co.
Tullia BattaglioliDepartment of Public Health, Institute of Tropical Medicine, St. Rochusstraat 43, 2000, Antwerp, Belgium.
Addys Díaz PiñeraCentro de Epidemiología y Salud Ambiental, Instituto Nacional de Higiene, Epidemiología y Microbiología (INHEM), Infanta No. 1158 e/ Llinás y Clavel, Centro Habana, 10300, La Habana, Cuba.
Armando Rodríguez SalváCentro de Epidemiología y Salud Ambiental, Instituto Nacional de Higiene, Epidemiología y Microbiología (INHEM), Infanta No. 1158 e/ Llinás y Clavel, Centro Habana, 10300, La Habana, Cuba.
Tom SmekensDepartment of Public Health, Institute of Tropical Medicine, St. Rochusstraat 43, 2000, Antwerp, Belgium.
Fernando Achiong EstupiñánCentro Provincial de Higiene y Epidemiología, Buena Vista esquina Milanés, Matanzas, Cuba.
Isabel Carbonell GarcíaCentro Provincial de Higiene y Epidemiología, Calle J No. 1 entre 1ra y 2da Reparto Sueño, Santiago de Cuba, Cuba.
Patrick Van der StuyftFaculty of Medicine and Health Sciences, Department of Public Health and Primary Care, Ghent University. Campus UZ-Ghent, Corneel Heymanslaan 10, 9000, Ghent, Belgium.
Instituto Nacional de Higiene, Epidemiología y Microbiología · CUGhent University · BEInstituut voor Tropische Geneeskunde · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundImplementation research to improve hypertension control is scarce in Latin America. We assessed the effectiveness of an intervention aimed at primary care practitioners and hypertensive patients in a setting that provides integrated care through an accessible network of family practices.

methodsWe conducted in Cardenas and Santiago, Cuba, a controlled before-after study in 122 family practices, which are staffed with a doctor and a nurse. The intervention comprised a control arm (usual care), an arm with a component targeting providers (hypertension management workshops), and an arm with, on top of the latter, a component targeting patients (hypertension schools). To evaluate the effect, we undertook a baseline survey before the intervention and an endline survey sixteen months after its start. In each survey, we randomly included 1400 hypertensive patients. Controlled hypertension, defined as a mean systolic and diastolic blood pressure below 140 and 90 mmHg, respectively, was the primary endpoint assessed. We performed linear and logistic regression with a Generalized Estimating Equations approach to determine if the proportion of patients with controlled hypertension changed following the intervention.

resultsSeventy-three doctors, including substitutes, and 54 nurses from the 61 intervention family practices attended the provider workshops, and 3308 patients -51.6% of the eligible ones- participated in the hypertension schools. Adherence to anti-hypertensive medication improved from 42% at baseline to 63% at the endline in the intervention arms. Under the provider intervention, the proportion of patients with controlled hypertension increased by 18.9%, from 48.7% at baseline to 67.6% at endline. However, adding the component that targeted hypertensive patients did not augment the effect. Compared to patients in the control arm, the adjusted OR of having controlled hypertension was 2.36 (95% CI, 1.73-3.22) in the provider and 2.00 (95% CI, 1.68-2.37) in the provider plus patient intervention arm.

conclusionsThe intervention's patient component remains to be fine-tuned. Still, we demonstrate that it is feasible to substantially improve hypertension outcomes by intervention at the primary care level, despite an already relatively high control rate.

Indexed as

HypertensionBlood PressureControlled Before-After StudiesCubaHumansPrimary Health CareChronic diseasesCubaFamily practiceHypertensionImplementation researchLatin AmericaPrimary health care

Identifiers

PMID36641434
PMCPMC9840256
OpenAlexW4316096546

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.