Evidence map›Paper›PMID 36640770›Full record

ReviewMolecular cell2023

Elucidating the structure and function of the nucleus-The NIH Common Fund 4D Nucleome program.

Ananda L Roy, Richard S Conroy, Veronica G Taylor, Judy Mietz, Ian M Fingerman, Michael J Pazin, Phillip Smith, Carolyn M Hutter, Dinah S Singer, Elizabeth L Wilder

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Molecular cell, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Viral remodeling of the 4D nucleome.Experimental & molecular medicine · 2024
    Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ananda L RoyOffice of Strategic Coordination, National Institutes of Health, Bethesda, MD 20892, USA; Division of Program Coordination, Planning, and Strategic Initiative, National Institutes of Health, Bethesda, MD 20892, USA; Office of the National Institutes of Health Director, National Institutes of Health, Bethesda, MD 20892, USA. Electronic address: ananda.roy@nih.gov.
Richard S ConroyOffice of Strategic Coordination, National Institutes of Health, Bethesda, MD 20892, USA; Division of Program Coordination, Planning, and Strategic Initiative, National Institutes of Health, Bethesda, MD 20892, USA; Office of the National Institutes of Health Director, National Institutes of Health, Bethesda, MD 20892, USA.
Veronica G TaylorOffice of Strategic Coordination, National Institutes of Health, Bethesda, MD 20892, USA; Division of Program Coordination, Planning, and Strategic Initiative, National Institutes of Health, Bethesda, MD 20892, USA; Office of the National Institutes of Health Director, National Institutes of Health, Bethesda, MD 20892, USA.
Judy MietzNational Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Ian M FingermanNational Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Michael J PazinNational Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Phillip SmithNational Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, MD 20892, USA.
Carolyn M HutterNational Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Dinah S SingerNational Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Elizabeth L WilderOffice of Strategic Coordination, National Institutes of Health, Bethesda, MD 20892, USA; Division of Program Coordination, Planning, and Strategic Initiative, National Institutes of Health, Bethesda, MD 20892, USA; Office of the National Institutes of Health Director, National Institutes of Health, Bethesda, MD 20892, USA.

Funding

Intramural NIH HHS Z99 OD999999
6 · The paper itself

Abstract

Genomic architecture appears to play crucial roles in health and a variety of diseases. How nuclear structures reorganize over different timescales is elusive, partly because the tools needed to probe and perturb them are not as advanced as needed by the field. To fill this gap, the National Institutes of Health Common Fund started a program in 2015, called the 4D Nucleome (4DN), with the goal of developing and ultimately applying technologies to interrogate the structure and function of nuclear organization in space and time.

Indexed as

Cell NucleusGenomeGenomicsUnited States

Identifiers

PMID36640770
PMCPMC9898192

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.