Evidence map›Paper›PMID 36640753›Full record

ArticleMed (New York, N.Y.)2023

The potential of auto-antigen-guided treatment of immune checkpoint inhibitor-mediated myocarditis.

Han Zhu, Yuhsin Vivian Huang, Sean M Wu

Open access · bronzeAbstract readComment
PubMed Publisher
In one paragraph

Article in Med (New York, N.Y.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 100% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Han ZhuStanford Cardiovascular Institute, Stanford University, Stanford, CA, USA; Department of Medicine, Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA, USA; Stanford University School of Medicine, Stanford, CA, USA.
Yuhsin Vivian HuangStanford Cardiovascular Institute, Stanford University, Stanford, CA, USA.
Sean M WuStanford Cardiovascular Institute, Stanford University, Stanford, CA, USA; Department of Medicine, Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA, USA; Stanford University School of Medicine, Stanford, CA, USA. Electronic address: smwu@stanford.edu.
Cardiovascular Institute of the South · US

Funding

From proteins to cells to tissues: A multi-scale assessment of biomechanical regulation by the myosin molecular motorRM1GM131981 · NIGMS · STANFORD UNIVERSITY · PI BERNSTEIN, DANIEL, MACK, DAVID LEE · 2019 to 2023
$10.3M
Identification of Causal Antigens in Immune Checkpoint Inhibitor-Induced MyocarditisF32HL149188 · NHLBI · STANFORD UNIVERSITY · PI ZHU, HAN · 2019 to 2020
$90k
NHLBI NIH HHS F32 HL149188NIGMS NIH HHS RM1 GM131981
6 · The paper itself

Abstract

Immune checkpoint inhibitor (ICI)-mediated myocarditis is a rare but devastating side effect of cancer immunotherapy with up to 40% mortality and long-term cardiac issues such as arrhythmias and heart failure in affected patients.

Indexed as

Antineoplastic Agents, ImmunologicalMyocarditisHumansImmune Checkpoint InhibitorsImmunotherapyAntineoplastic Agents, ImmunologicalImmune Checkpoint Inhibitors

Identifiers

PMID36640753
OpenAlexW4315874234

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.