Evidence map›Paper›PMID 36640747›Full record

ArticleClinical biomechanics (Bristol, Avon)2023

Carpal arch space increased by volar force applied to the skin surface above the carpal tunnel.

Hui Zhang, David Jordan, Zong-Ming Li

Open access · greenAbstract read
In one paragraph

Article in Clinical biomechanics (Bristol, Avon), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Hui ZhangHand Research Laboratory, Department of Orthopaedic Surgery and Arthritis Center, University of Arizona College of Medicine, Tucson, USA.
David JordanHand Research Laboratory, Department of Orthopaedic Surgery and Arthritis Center, University of Arizona College of Medicine, Tucson, USA.
Zong-Ming LiHand Research Laboratory, Department of Orthopaedic Surgery and Arthritis Center, University of Arizona College of Medicine, Tucson, USA; Department of Biomedical Engineering, University of Arizona, Tucson, USA. Electronic address: lizongming@arizona.edu.
University of Arizona · US

Funding

Biomechanical Treatment of Carpal Tunnel SyndromeR01AR068278 · NIAMS · UNIVERSITY OF ARIZONA · PI LI, ZONG-MING · 2015 to 2019
$2.8M
NIAMS NIH HHS R01 AR068278
6 · The paper itself

Abstract

backgroundCarpal arch space augmentation can help decompress the median nerve. The augmentation can be achieved by mechanical manipulations utilizing the biomechanics of the tunnel structure. The purpose of this study was to expand the carpal arch in vitro by applying volar forces on the surface of the wrist.

methodsThe mechanism was implemented in eight cadaver hands by attaching a volar force transmitter to the palmar surface of the wrist and pulling the transmitter volarly at six force levels (0, 3, 6, 9, 12, and 15 N). Ultrasound images of the cross section at the distal carpal tunnel were collected for morphological analysis.

findingsThe carpal arch height, width, and area were significantly altered by the volarly applied force (P < 0.001). The arch height and area were increased but the arch width was decreased by the force. Pearson's correlation coefficient showed that there was a positive correlation between the arch height and force magnitude; and between the arch area and force magnitude. A negative correlation existed between the arch width and force magnitude (P < 0.001). The magnitude of change of the arch height, width, and area was increased as the force magnitude increased.

interpretationThis study demonstrated that applying external forces on the wrist skin to increase the carpal arch space was feasible. The magnitude of the force influenced its effect on altering the carpal arch. Study limitations include small sample size and inclusion of male specimens. Future in vivo work is needed for clinical translation feasibility.

Indexed as

Carpal BonesCarpal Tunnel SyndromeHumansMaleMedian NerveWristWrist JointCarpal arch spaceUltrasonographyVolar forceWrist skin

Identifiers

PMID36640747
PMCPMC9975036
OpenAlexW4315499093

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.