Evidence map›Paper›PMID 36640457›Full record

Trial reportBehaviour research and therapy2023

Mechanisms of cognitive behavioral therapy vs. supportive psychotherapy in body dysmorphic disorder: An exploratory mediation analysis.

Jennifer L Greenberg, Katharine A Phillips, Susanne S Hoeppner, Nicholas C Jacobson, Angela Fang, Sabine Wilhelm

Open access · greenAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Behaviour research and therapy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
2.8field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Jennifer L GreenbergMassachusetts General Hospital and Harvard Medical School, 185 Cambridge Street, Suite 2000, Boston, MA, 02114, USA. Electronic address: jlgreenberg@mgh.harvard.edu.
Katharine A PhillipsRhode Island Hospital and Alpert Medical School of Brown University, 222 Richmond St, Providence, RI, 02903, USA; New York-Presbyterian Hospital and Weill Cornell Medical College, 315 East 62nd Street, New York, NY, 10065, USA. Electronic address: kap9161@med.cornell.edu.
Susanne S HoeppnerMassachusetts General Hospital and Harvard Medical School, 185 Cambridge Street, Suite 2000, Boston, MA, 02114, USA. Electronic address: shoeppner@mgh.harvard.edu.
Nicholas C JacobsonMassachusetts General Hospital and Harvard Medical School, 185 Cambridge Street, Suite 2000, Boston, MA, 02114, USA; Geisel School of Medicine at Dartmouth College, 46 Centerra Parkway, EverGreen Center, Suite 315, Lebanon, NH, 03766, USA. Electronic address: Nicholas.C.Jacobson@dartmouth.edu.
Angela FangMassachusetts General Hospital and Harvard Medical School, 185 Cambridge Street, Suite 2000, Boston, MA, 02114, USA; University of Washington, 3751 West Stevens Way NE, Seattle, WA, 98195, USA. Electronic address: angfang@uw.edu.
Sabine WilhelmMassachusetts General Hospital and Harvard Medical School, 185 Cambridge Street, Suite 2000, Boston, MA, 02114, USA. Electronic address: swilhelm@mgh.harvard.edu.
Massachusetts General Hospital · USCambridge Hospital · USDartmouth College · USNewYork–Presbyterian Hospital · US

Funding

1/2-CBT Versus Supportive Psychotherapy for Body Dysmorphic DisorderR01MH091078 · NIMH · MASSACHUSETTS GENERAL HOSPITAL · PI WILHELM, SABINE · 2011 to 2015
$2.0M
2/2-CBT Versus Supportive Psychotherapy for Body Dysmorphic DisorderR01MH091023 · NIMH · RHODE ISLAND HOSPITAL · PI PHILLIPS, KATHARINE ANNE · 2011 to 2015
$1.6M
NIMH NIH HHS R01 MH091023NIMH NIH HHS R01 MH091078
6 · The paper itself

Abstract

Body dysmorphic disorder (BDD) is common, severe, and often chronic. Cognitive behavioral therapy (CBT) is the first-line psychosocial treatment for BDD, with well-established efficacy. However, some patients do not improve with CBT, and little is known about how CBT confers its effects. Neurocognitive processes have been implicated in the etiology and maintenance of BDD and are targeted by CBT-BDD treatment components. Yet, the malleability of these factors in BDD, and their potential role in mediating symptom improvement, are not well understood. Understanding how treatment works could help optimize treatment outcomes. In this secondary data analysis of a randomized clinical trial of CBT vs. supportive psychotherapy (SPT) in BDD (n = 120), we examined whether treatment-related changes in detail processing (Rey-Osterrieth Complex Figure test), maladaptive appearance beliefs (Appearance Schemas Inventory-Revised), and emotion recognition (Emotion Recognition Task) mediated treatment outcome. All constructs improved over time and were associated with symptom improvement. CBT was associated with greater improvements in maladaptive beliefs than SPT. None of the variables examined mediated symptom improvement. Findings suggest that with successful treatment, individuals with BDD demonstrate reduced neurocognitive deficits (detail processing, emotion recognition, maladaptive beliefs) and that CBT is more likely than SPT to improve maladaptive appearance beliefs. More work is needed to understand mechanisms of change and thus maximize treatment outcomes.

Indexed as

Body Dysmorphic DisordersCognitive Behavioral TherapyHumansMediation AnalysisPsychotherapyTreatment OutcomeBody dysmorphic disorderCognitive behavioral therapyInformation processingMechanismsMediatorsNeurocognitive

Identifiers

PMID36640457
PMCPMC9892287
OpenAlexW4313856673

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.