Evidence map›Paper›PMID 36640135›Full record

ArticleJournal of animal science2023

Feeding a Saccharomyces cerevisiae fermentation product before and during a feed restriction challenge on milk production, plasma biomarkers, and immune function in Holstein cows.

Danielle N Coleman, Qianming Jiang, Matheus G Lopes, Luciano Ritt, Yusheng Liang, Ahmad Aboragah, Erminio Trevisi, Ilkyu Yoon, Juan J Loor

Open access · hybridAbstract read
In one paragraph

Article in Journal of animal science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
4.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

  1. Effect ofMicrobiology spectrum · 2026
    Article
  2. Review
  3. Article
  4. The Effect ofAnimals : an open access journal from MDPI · 2024
    Article
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 3 countries.

Danielle N ColemanDepartment of Animal Sciences, Division of Nutritional Sciences, University of Illinois, Urbana, IL 61801, USA.
Qianming JiangDepartment of Animal Sciences, Division of Nutritional Sciences, University of Illinois, Urbana, IL 61801, USA.ORCID 0000-0001-9522-4856
Matheus G LopesDepartment of Animal Sciences, Division of Nutritional Sciences, University of Illinois, Urbana, IL 61801, USA.
Luciano RittDepartment of Animal Sciences, Division of Nutritional Sciences, University of Illinois, Urbana, IL 61801, USA.
Yusheng LiangDepartment of Animal Sciences, Division of Nutritional Sciences, University of Illinois, Urbana, IL 61801, USA.
Ahmad AboragahDepartment of Animal Sciences, Division of Nutritional Sciences, University of Illinois, Urbana, IL 61801, USA.
Erminio TrevisiDepartment of Animal Sciences, Food and Nutrition (DIANA), Research Center Romeo and Enrica Invernizzi for sustainable dairy production (CREI), Faculty of Agriculture, Food and Environmental Science, Università Cattolica del Sacro Cuore, 29122 Piacenza, Italy.
Ilkyu YoonDiamond V, Cedar Rapids, IA 52404, USA.
Juan J LoorDepartment of Animal Sciences, Division of Nutritional Sciences, University of Illinois, Urbana, IL 61801, USA.ORCID 0000-0003-1586-4365
University of Illinois Urbana-Champaign · USDiamond V (United States) · USUniversidade Federal do Rio Grande do Sul · BRUniversità Cattolica del Sacro Cuore · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Periods of decreased feed intake may disrupt function of the intestinal barrier. Feeding NutriTek® (NTK; Diamond V, Cedar Rapids, IA), a postbiotic from S. cerevisiae fermentation (SCFP), improved health and supported anti-inflammatory functions. We investigated the effects of feeding NTK to cows before and during a period of feed restriction (FR) designed to model periods of intestinal barrier dysfunction. In total, 16 multiparous cows (97.1 ± 7.6 DIM; n = 8/group) were fed a control diet (CON) or CON plus 19 g/d NTK for 9 wk (Phase 1; P1) and then were subjected to an FR challenge for 5 d, during which they were fed 40% of their ad libitum intake from the 7 d prior to FR. Milk yield (MY) and DMI were collected daily. During FR, milk was collected daily for composition, blood daily to measure plasma biomarkers and to measure monocyte and neutrophil phagocytosis and oxidative burst on d 1, 3, and 5. Data were analyzed using a mixed model in SAS 9.4. All data were subjected to repeated measures ANOVA. Dietary treatment (TRT), Day, and their interaction (TRT × Day) were considered as fixed effects and cow as the random effect. For analysis of P1, data collected during a 7-d adaptation phase were used as a covariate. During P1, NTK cows tended to have greater DMI and had greater fat, ECM and FCM yields, and feed efficiency (ECM/DMI and FCM/DMI). Protein yield tended to be greater in NTK compared with CON cows. A tendency for greater monocyte phagocytosis was detected with NTK. However, during FR, feeding NTK led to lower MY and lactose yield and tended to lower solids percentage. While NTK cows tended to have reduced neutrophil oxidative burst than CON cows during FR (NTK: 26.20%, CON: 36.93%), there was no difference in phagocytosis (NTK: 7.92%, CON: 6.31%). Plasma biomarkers of energy metabolism, liver function, inflammation, and oxidative stress during the FR period did not differ. Overall, results suggested that feeding NTK increased the yield of FCM, ECM, feed efficiency and milk components prior to FR.

Indexed as

MilkSaccharomyces cerevisiaeAnimal FeedAnimalsCattleDietDietary SupplementsFemaleFermentationLactationPhagocytosisfeed restrictionimmune functionlactationleaky gut

Identifiers

PMID36640135
PMCPMC9992451
OpenAlexW4316097072

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.