Evidence map›Paper›PMID 36639940›Full record

ArticlePharmacology research & perspectives2023

Comparative evaluation of biased agonists Sarcosine

Natalia M Noto, Yazmin M Restrepo, Hong W Pang, Filipe Stoyell-Conti, Crystal A West, Robert C Speth

Open access · goldAbstract read
In one paragraph

Article in Pharmacology research & perspectives, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Insights Into the Role of Angiotensin-II ATHypertension (Dallas, Tex. : 1979) · 2024
    Review
  3. Comparative evaluation of biased agonists SarcosinePharmacology research & perspectives · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Natalia M NotoCollege of Pharmacy, Nova Southeastern University, Fort Lauderdale, Florida, USA.
Yazmin M RestrepoCollege of Pharmacy, Nova Southeastern University, Fort Lauderdale, Florida, USA.
Hong W PangCollege of Pharmacy, Nova Southeastern University, Fort Lauderdale, Florida, USA.
Filipe Stoyell-ContiCollege of Pharmacy, Nova Southeastern University, Fort Lauderdale, Florida, USA.
Crystal A WestDepartment of Biology, Appalachian State University, Kannapolis, North Carolina, USA.
Robert C SpethCollege of Pharmacy, Nova Southeastern University, Fort Lauderdale, Florida, USA.ORCID 0000-0002-6434-2136
Nova Southeastern University · USAppalachian State University · USGeorgetown University · USUniversity of Miami · US

Funding

Brain pathophysiology in SARS-CoV-2 diseaseR01NS124204 · NINDS · GEORGETOWN UNIVERSITY · PI SANDBERG, KATHRYN L · 2021 to 2025
$3.1M
NINDS NIH HHS R01 NS124204
6 · The paper itself

Abstract

Angiotensin II analogue and β-arrestin biased agonist TRV027 (Sarcosine

Indexed as

Angiotensin IILiverReceptor, Angiotensin, Type 1SarcosineAlanineAnimalsbeta-ArrestinsFemaleIsoleucineMaleRatsAlanineAngiotensin IIbeta-ArrestinsIsoleucineReceptor, Angiotensin, Type 1SarcosineAT1Rbinding assayd-Alanine8-Angiotensin IIGPCRSarcosine1, Isoleucine8-Angiotensin IITRV027

Identifiers

PMID36639940
PMCPMC9840060
OpenAlexW4316174745

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.