Evidence map›Paper›PMID 36639899›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2023

Histamine Release in the Prefrontal Cortex Excites Fast-Spiking Interneurons while GABA Released from the Same Axons Inhibits Pyramidal Cells.

Diana Lucaci, Xiao Yu, Paul Chadderton, William Wisden, Stephen G Brickley

Open access · greenAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Metabolic Messengers: ketone bodies.Nature metabolism · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Diana LucaciDepartment of Life Sciences, Imperial College London, London SW7 2AZ, United Kingdom.
Xiao YuDepartment of Life Sciences, Imperial College London, London SW7 2AZ, United Kingdom.
Paul ChaddertonSchool of Physiology, Pharmacology and Neuroscience, University of Bristol, Bristol, United Kingdom.ORCID 0000-0002-6276-1011
William WisdenDepartment of Life Sciences, Imperial College London, London SW7 2AZ, United Kingdom.ORCID 0000-0003-4743-0334
Stephen G BrickleyDepartment of Life Sciences, Imperial College London, London SW7 2AZ, United Kingdom s.brickley@imperial.ac.uk.ORCID 0000-0002-0930-7346
Imperial College London · GBUK Dementia Research Institute · GBUniversity of Bristol · GB

Funding

Biotechnology and Biological Sciences Research Council BB/N008871/1Wellcome Trust 107841Wellcome Trust 209453/Z/17/ZWellcome Trust 220759
6 · The paper itself

Abstract

We studied how histamine and GABA release from axons originating from the hypothalamic tuberomammillary nucleus (TMN) and projecting to the prefrontal cortex (PFC) influence circuit processing. We optostimulated histamine/GABA from genetically defined TMN axons that express the histidine decarboxylase gene (TMN

Indexed as

HistamineHistamine ReleaseAction PotentialsAnimalsAxonsFemalegamma-Aminobutyric AcidInterneuronsMaleMicePrefrontal CortexPyramidal Cellsgamma-Aminobutyric AcidHistamineGABAhistaminehypothalamusprefrontal cortex

Identifiers

PMID36639899
PMCPMC9838703
OpenAlexW4311883466

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.