Evidence map›Paper›PMID 36639786›Full record

ArticleGenes and environment : the official journal of the Japanese Environmental Mutagen Society2023

Effects of plasma-activated Ringer's lactate solution on cancer cells: evaluation of genotoxicity.

Yang Liu, Yoshimichi Nakatsu, Hiromasa Tanaka, Kazunori Koga, Kenji Ishikawa, Masaharu Shiratani, Masaru Hori

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Genes and environment : the official journal of the Japanese Environmental Mutagen Society, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Yang LiuGraduate School of Engineering, Nagoya University, Furo-cho, Chikusa-ku, Nagoya, 464-8603, Japan. liu.yang.f1@s.mail.nagoya-u.ac.jp.ORCID http://orcid.org/0000-0003-1475-9651
Yoshimichi NakatsuGraduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Hiromasa TanakaCenter for Low-temperature Plasma Sciences, Nagoya University, Nagoya, Japan.
Kazunori KogaCenter for Low-temperature Plasma Sciences, Nagoya University, Nagoya, Japan.
Kenji IshikawaCenter for Low-temperature Plasma Sciences, Nagoya University, Nagoya, Japan.
Masaharu ShirataniCenter for Low-temperature Plasma Sciences, Nagoya University, Nagoya, Japan.
Masaru HoriCenter for Low-temperature Plasma Sciences, Nagoya University, Nagoya, Japan.
Nagoya University · JPKyushu University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNon-thermal atmospheric pressure plasma technologies form the core of many scientific advances, including in the electronic, industrial, and biotechnological fields. The use of plasma as a cancer therapy has recently attracted significant attention due to its cancer cell killing activity. Plasma-activated Ringer's lactate solution (PAL) exhibits such activity. In addition to ROS, PAL contains active compounds or species that cause cancer cell death, but the potential mutagenic risks of PAL have not been studied.

resultsPAL has a low pH value and a high concentration of H

conclusionPAL contains one or more active compounds or species in addition to H

Indexed as

CytotoxicityGenotoxicityPAL

Identifiers

PMID36639786
PMCPMC9837981
OpenAlexW4315864751

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.