ArticleBMC geriatrics2023
Predictors of incident reversible and potentially reversible cognitive frailty among Taiwanese older adults.
Article in BMC geriatrics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.
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Who cites it
15 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Cognitive frailty risk prediction models in patients with chronic kidney disease in China: a systematic review and meta-analysis.BMC nephrology · 2026Pooled it
- Concurrent Validity Evidence for Pressure-Sensing Walkways Measuring Spatiotemporal Features of Gait: A Systematic Review and Meta-Analysis.Sensors (Basel, Switzerland) · 2024Pooled it
- Article
- A longitudinal study on multiple frailty and its associations with depression and social participation in older adults.Scientific reports · 2026Article
- Association between physical performance and cognitive frailty in middle-aged and older adults undergoing maintenance hemodialysis: a cross-sectional study.Scientific reports · 2026Article
- Association Rule Analysis of Cognitive Frailty Subtypes in Community-Dwelling Older Adults.Clinical interventions in aging · 2026Article
- Linking Motor and Cognitive Decline in Aging: Gait Variability and Working Memory as Early Markers of Frailty.Healthcare (Basel, Switzerland) · 2025Article
- Article
- Predicting cognitive frailty in community-dwelling older adults: a machine learning approach based on multidomain risk factors.Scientific reports · 2025Article
- Association of multimorbidity patterns and order of physical frailty and cognitive impairment occurrence: a prospective cohort study.Age and ageing · 2025Article
- Convergent and predictive validity of the activities-specific balance confidence scales and balance recovery confidence scale, with regard to the falls efficacy scale-international: a cross-sectional study.Frontiers in aging · 2025Article
- Development and validation of a predictive model for cognitive frailty in community-dwelling older adults: a cross-sectional study.Frontiers in public health · 2025Article
- Biological and Physical Performance Markers for Early Detection of Cognitive Impairment in Older Adults.Journal of clinical medicine · 2024Review
- Factors affecting cognitive frailty improvement and progression in Taiwanese older adults.BMC geriatrics · 2024Article
- Development and validation of a cognitive dysfunction risk prediction model for the abdominal obesity population.Frontiers in endocrinology · 2024Article
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5 authors.
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Abstract
backgroundFew studies emphasize on predictors of incident cognitive frailty (CF) and examine relationships between various gait characteristics and CF. Therefore, we conducted a 2-year prospective study to investigate potential predictors, including gait characteristics, of incident reversible CF (RCF) and potentially RCF (PRCF) among Taiwanese older adults.
methodsEligible participants were individuals aged ≥ 65 years, who could ambulate independently, and did not have RCF/PRCF at the baseline. The baseline assessment collected information on physical frailty and cognitive measures, in addition to sociodemographic and lifestyle characteristics, preexisting comorbidities and medications, gait characteristics, Tinetti's balance, balance confidence as assessed by Activities-specific Balance Confidence (ABC) scale, and the depressive status as assessed by the Geriatric Depression Scale. The Mini-Mental State Examination (MMSE), Mattis Dementia Rating Scale, and Digit Symbol Substitution Test were used to evaluate cognitive functions. Incident RCF and PRCF were ascertained at a 2-year follow-up assessment.
resultsResults of the multinomial logistic regression analysis showed that incident RCF was significantly associated with older age (odds ratio [OR] = 1.05) and lower ABC scores (OR = 0.97). Furthermore, incident PRCF was significantly associated with older age (OR = 1.07), lower ABC scores (OR = 0.96), the presence of depression (OR = 3.61), lower MMSE scores (OR = 0.83), slower gait velocity (OR = 0.97), and greater double-support time variability (OR = 1.09).
conclusionsIncident RCF was independently associated with older age and lower balance confidence while incident PRCF independently associated with older age, reduced global cognition, the presence of depression, slower gait velocity, and greater double-support time variability. Balance confidence was the only modifiable factor associated with both incident RCF and PRCF.
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