Evidence map›Paper›PMID 36639663›Full record

ArticleJournal of neuroinflammation2023

Blocking interleukin-23 ameliorates neuromuscular and thymic defects in myasthenia gravis.

José A Villegas, Jérôme Van Wassenhove, Judith Merrheim, Karen Matta, Samy Hamadache, Clémence Flaugère, Pauline Pothin, Frédérique Truffault, Sébastien Hascoët, Nicola Santelmo and 4 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of neuroinflammation, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Targeting pathogenic Th17.1 cells via JAK-STAT3 pathway: A novel approach with tofacitinib for refractory myasthenia gravis.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 6 institutions in 1 country.

José A VillegasInserm, Institut de Myologie, Centre de Recherche en Myologie, Sorbonne Université, 105 Bd de l'hôpital, 75013, Paris, France.
Jérôme Van WassenhoveInserm, Institut de Myologie, Centre de Recherche en Myologie, Sorbonne Université, 105 Bd de l'hôpital, 75013, Paris, France.
Judith MerrheimInserm, Institut de Myologie, Centre de Recherche en Myologie, Sorbonne Université, 105 Bd de l'hôpital, 75013, Paris, France.
Karen MattaInserm, Institut de Myologie, Centre de Recherche en Myologie, Sorbonne Université, 105 Bd de l'hôpital, 75013, Paris, France.
Samy HamadacheInserm, Institut de Myologie, Centre de Recherche en Myologie, Sorbonne Université, 105 Bd de l'hôpital, 75013, Paris, France.
Clémence FlaugèreInserm, Institut de Myologie, Centre de Recherche en Myologie, Sorbonne Université, 105 Bd de l'hôpital, 75013, Paris, France.
Pauline PothinInserm, Institut de Myologie, Centre de Recherche en Myologie, Sorbonne Université, 105 Bd de l'hôpital, 75013, Paris, France.
Frédérique TruffaultInserm, Institut de Myologie, Centre de Recherche en Myologie, Sorbonne Université, 105 Bd de l'hôpital, 75013, Paris, France.
Sébastien HascoëtHôpital Marie Lannelongue, Le Plessis-Robinson, France.
Nicola SantelmoChirurgie Thoracique des deux Rives, Rhéna - Clinique de Strasbourg, Strasbourg, France.
Marco AlifanoDepartment of Pathology, Cochin University Hospital Group, AP-HP, Paris-Descartes University, Paris, France.
Sonia Berrih-AkninInserm, Institut de Myologie, Centre de Recherche en Myologie, Sorbonne Université, 105 Bd de l'hôpital, 75013, Paris, France.
Rozen le PanseInserm, Institut de Myologie, Centre de Recherche en Myologie, Sorbonne Université, 105 Bd de l'hôpital, 75013, Paris, France.
Nadine DraginInserm, Institut de Myologie, Centre de Recherche en Myologie, Sorbonne Université, 105 Bd de l'hôpital, 75013, Paris, France. nadine.dragin-mamavi@upmc.fr.
Centre de Recherche en MyologieInserm · FRSorbonne Université · FRInstitut de Myologie · FRHôpital Marie Lannelongue · FRUniversité Paris Cité · FR

Funding

European Commission HEALTH-2009-242-210
6 · The paper itself

Abstract

Acetylcholine receptor (AChR) myasthenia gravis (MG) is a chronic autoimmune disease characterized by muscle weakness. The AChR

Indexed as

Interleukin-23Myasthenia Gravis, Autoimmune, ExperimentalAnimalsAutoantibodiesHumansInterleukin-23 Subunit p19MiceNeuromuscular JunctionReceptors, CholinergicAutoantibodiesInterleukin-23Interleukin-23 Subunit p19Receptors, CholinergicAutoimmunityGerminal centersInflammationMuscle regenerationNeuromuscular junctionTh17

Identifiers

PMID36639663
PMCPMC9837970
OpenAlexW4315853765

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.