Evidence map›Paper›PMID 36639518›Full record

ArticlePediatric research2023

Child and family factors associated with positive outcomes among youth born extremely preterm.

Crisma Emmanuel, Joe X Yi, Robert M Joseph, Karl K C Kuban, Kathy A Knafl, Sharron L Docherty, Eric A Hodges, Rebecca C Fry, T Michael O'Shea, Hudson P Santos

Abstract read
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In one paragraph

Article in Pediatric research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
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0citing papers in PubMed
–field-weighted citation impact, top 99% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Crisma EmmanuelSchool of Nursing, University of North Carolina, Chapel Hill, NC, USA. emmanc@email.unc.edu.ORCID 0000-0003-2247-9844
Joe X YiGillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Robert M JosephSchool of Medicine, Boston University, Boston, MA, USA.
Karl K C KubanSchool of Medicine, Boston University, Boston, MA, USA.
Kathy A KnaflSchool of Nursing, University of North Carolina, Chapel Hill, NC, USA.
Sharron L DochertySchool of Nursing, Duke University, Durham, NC, USA.
Eric A HodgesSchool of Nursing, University of North Carolina, Chapel Hill, NC, USA.
Rebecca C FryGillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
T Michael O'SheaSchool of Medicine, University of North Carolina, Chapel Hill, NC, USA.
Hudson P SantosNursing, University of Miami, Coral Gables, USA.
University of North Carolina at Chapel Hill · USBoston University · USDuke University · USUniversity of Miami · US

Funding

Neonatal Biomarkers in Extremely Preterm Babies Predict Childhood Brain DisordersU01NS040069 · NINDS · CHILDREN'S HOSPITAL BOSTON · PI KUBAN, KARL · 2001 to 2014
$34.0M
Environment, Epigenetics, Neurodevelopment & Health of Extremely Preterm ChildrenUG3OD023348 · OD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI FRY, REBECCA, O'SHEA, MICHAEL · 2016 to 2024
$7.4M
Placental Epigenome and Brain Dysfunction after Preterm BirthR01HD092374 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI FRY, REBECCA, O'SHEA, MICHAEL · 2017 to 2021
$3.2M
Genetic and Epigenetic Effects on Childhood Cognitive TrajectoriesR01NR019245 · NINR · UNIV OF NORTH CAROLINA CHAPEL HILL · PI SANTOS, HUDSON · 2020 to 2024
$1.7M
NICHD NIH HHS R01 HD092374NIH HHS UG3 OD023348NINDS NIH HHS U01 NS040069NINR NIH HHS R01 NR019245
6 · The paper itself

Abstract

backgroundTo analyze the relationship of child behavioral and communication disorders, and adverse family events, to later-in-life child health and cognitive function among youth born extremely preterm.

methodsThe study participants were 694 children enrolled in the Extremely Low Gestational Age Newborn Study. At ages 2 and 10, we assessed internalizing and externalizing behaviors, and at age 10, we assessed adverse life events within the family. Associations were evaluated between these child and family factors and positive child health at age 10 years, and global health and cognitive function at age 15 years.

resultsLower T-scores for internalizing or externalizing behaviors at age 2 were associated with more positive health at age 10. The absence of internalizing behaviors at age 10 was associated with better global child health and better cognitive function at age 15. The absence of communication deficits at age 10 was associated with better cognitive function at age 15. The absence of parent job loss was associated with better global child health at age 15.

conclusionAmong individuals born extremely preterm, child health and cognitive outcomes might be improved by timely interventions to address child behavioral symptoms and the impact of adverse life events in the family. IMPACT: The absence of child behavioral and communication disorders, and adverse family events, were associated with more positive health, higher global health, and better cognitive function among youth born extremely preterm. Interventions to address behavioral disorders in early childhood, and to reduce the impact of adverse life events on the family, might promote improved health and developmental outcomes for adolescents born extremely preterm.

Indexed as

Child Behavior DisordersInfant, Extremely PrematureAdolescentChildChild BehaviorChild, PreschoolFemaleGestational AgeHumansInfant, NewbornParturitionPregnancy

Identifiers

PMID36639518
OpenAlexW4316037289

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.